CD19 Antibodies

Gene Name: CD19 (Cluster of Differentiation 19)


Function: CD19 is a cell surface protein that is expressed throughout B cell development, from early pre-B cells to mature B cells. It plays a crucial role in B cell activation, proliferation, and differentiation. CD19 acts as a co-receptor along with the B cell receptor (BCR) complex to modulate B cell signaling and enhance B cell responses to antigens.

Immune Regulation: CD19 is involved in regulating various aspects of B cell function, including B cell activation, survival, and antibody production. It plays a critical role in maintaining peripheral B cell tolerance and preventing autoimmunity by promoting the elimination of autoreactive B cells through receptor editing or negative selection.

Apoptosis: While CD19 itself does not directly induce apoptosis, dysregulation of CD19 signaling can affect B cell survival and contribute to the pathogenesis of certain B cell malignancies, such as B-cell acute lymphoblastic leukemia (B-ALL) and non-Hodgkin lymphoma.

Research Implications: CD19 is a widely studied protein in immunology and cancer biology due to its central role in B cell development and function. Research on CD19 has provided insights into B cell signaling pathways, autoimmune diseases, and B cell malignancies.

Clinical Relevance: CD19 has emerged as a key target for immunotherapy in B cell malignancies. Antibody-based therapies targeting CD19, such as monoclonal antibodies and CAR-T cell therapies, have shown remarkable efficacy in the treatment of B-ALL, diffuse large B-cell lymphoma (DLBCL), and other CD19-positive malignancies. CAR-T cell therapies targeting CD19, in particular, have demonstrated high response rates and durable remissions in patients with relapsed/refractory B-ALL and DLBCL.

AffiAB®​ Anti-Human CD19-PE conjugate
CAT# AFG-APD-3817
Size: 100 tests
480.00 480.0 USD
AffiAB®​ Anti-Human CD19 FITC/CD2 PE
CAT# AFG-APD-3813
Size: 50 tests
720.00 720.0 USD
AffiAB®​ Anti-Human CD5 FITC/CD19 PE
CAT# AFG-APD-3746
Size: 50 tests
720.00 720.0 USD
AffiAB®​ Anti-Human CD3 FITC/CD19 PE/CD45 PE-Cy5
CAT# AFG-APD-3733
Size: 50 tests
720.00 720.0 USD
AffiAB®​ Anti-Human CD3 FITC/CD19 PE
CAT# AFG-APD-3727
Size: 50 tests
720.00 720.0 USD
AffiAB®​ Anti-Human CD2 FITC/CD19-PE
CAT# AFG-APD-3720
Size: 50 tests
720.00 720.0 USD
480.00 480.0 USD
624.55 624.5500000000001 USD
420.00 420.0 USD
624.55 624.5500000000001 USD
420.00 420.0 USD
624.55 624.5500000000001 USD
420.00 420.0 USD
AffiAB®​ CD19 (CVID3/429), 1mg/mL Antibody
CAT# AFG-BTM-02482
Size: 50 μL
624.55 624.5500000000001 USD
AffiAB®​ CD19 (CVID3/429), 0.2mg/mL Antibody
CAT# AFG-BTM-02481
Size: 100 μL
420.00 420.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
AffiAB®​ CD19 (CVID3/366), 1mg/mL Antibody
CAT# AFG-BTM-02094
Size: 50 μL
624.55 624.5500000000001 USD
AffiAB®​ CD19 (CVID3/366), 0.2mg/mL Antibody
CAT# AFG-BTM-02093
Size: 100 μL
420.00 420.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
AffiAB® Anti-CD19 Antibody (N-term)
CAT# AFG-BRB-22779
Size: 80 μL
293.10 293.1 USD
286.45 286.45 USD
253.20 253.20000000000002 USD
AffiAB® Anti-CD192 CCR2 Antibody
CAT# AFG-BRB-03032
Size: 100 μL
389.05 389.05 USD
142.05 142.05 USD
331.10 331.1 USD
285.50 285.5 USD
225.65 225.65 USD
224.70 224.70000000000002 USD
297.85 297.85 USD
AffiAB®​ Anti-Ms CD197 Purified [4B12]
CAT# AFG-XBO-2103
Size: 25 tests
162.00 162.0 USD
AffiAB®​ Anti-Ms CD197 PE [4B12]
CAT# AFG-XBO-2102
Size: 25 tests
181.00 181.0 USD
86.00 86.0 USD
AffiAB®​ Anti-Ms CD19 Purified [1D3]
CAT# AFG-XBO-2100
Size: 25 tests
86.00 86.0 USD
AffiAB®​ Anti-Ms CD19 PE [1D3]
CAT# AFG-XBO-2099
Size: 100 tests
162.00 162.0 USD
AffiAB® Rat anti-CD19 Antibody
CAT# AFG-DDA-9423
Size: 100 μL
284.05 284.05 USD
AffiAB® Mouse anti-CD19 Antibody
CAT# AFG-DDA-9352
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-CD19 Antibody
CAT# AFG-DDA-9241
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit Anti-CD19 (pY531) Antibody
CAT# AFG-DDA-6968
Size: 100 μL
319.20 319.2 USD
AffiAB® Rabbit anti-CD19 Antibody
CAT# AFG-DDA-2875
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-CD192 Antibody
CAT# AFG-DDA-1530
Size: 100 μL
274.55 274.55 USD