AffiAB®​ Anti-Ms CD19 Purified Low Endotoxin [1D3]

https://www.affiab.com/web/image/product.template/376115/image_1920?unique=ac75fb5
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CAT# AFG-XBO-2101
Size: 25 tests

86.00 86.0 USD 86.00

86.00

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Overview

CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity..

Species Reactivity

Mouse.

Antigen

CD19.

Negative Species

N/A.

Application

FC (QC tested), IP, IHC (F), FUNC) .

Immunogen

Mouse CD19-transfected cell line.

Clone

1D3.

Format

Purified Low Endotoxin.

Isotype

Rat IgG2a.

Storage Buffer

Phosphate buffered saline (PBS), pH 7.4.

Storage & Stability

Store at 2-8°C. Do not freeze.