AffiAB®​ CD19 (CVID3/366), CF405S conjugate, 0.1mg/mL Antibody

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CAT# AFG-BTM-02085
Size: 100 μL

380.00 380.0 USD 380.00

380.00

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Overview

CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate

CF405S.

Concentration

0.1 mg/mL.

Storage Buffer

PBS, 0.1% BSA, 0.05% azide.

Product Applications

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Storage Temperature

2°C to 8°C.

Stability

Stable at room temperature or 37°C (98°F) for 7 days.