CAR-T Cell Therapy Antibodies

CAR-T for Chimeric Antigen Receptor T-cell


  1. Immunomodulation: Antibodies could be developed to modulate the activity of CAR-T cells. This could involve enhancing their cytotoxic activity against cancer cells or regulating their proliferation and persistence in vivo.
  2. Inhibition of Off-Target Effects: CAR-T cell therapy can sometimes lead to off-target effects, where CAR-T cells attack healthy cells expressing the targeted antigen. Antibodies could potentially be used to block CAR-T cell interactions with unintended target cells, reducing toxicity.
  3. Regulation of CAR-T Cell Trafficking: Antibodies might be utilized to control the migration of CAR-T cells to specific tissues or tumor sites, optimizing their distribution within the body for enhanced therapeutic efficacy.
  4. Immunosuppression: In some cases, there may be a need to dampen the activity of CAR-T cells to prevent excessive immune responses or cytokine release syndrome (CRS). Antibodies targeting T-cell signaling pathways or inflammatory cytokines could potentially mitigate these adverse effects.
  5. Preclinical Research: Antibodies could serve as valuable tools for studying CAR-T cell biology and optimizing CAR-T cell therapy in preclinical models. They could be used to dissect signaling pathways, evaluate CAR-T cell interactions with tumor cells, and assess immune responses in vivo.
  6. Combination Therapies: Antibodies targeting immune checkpoint molecules, such as PD-1, CTLA-4, or LAG-3, could be combined with CAR-T cell therapy to enhance anti-tumor immunity. This approach aims to overcome immune suppression within the tumor microenvironment and improve the efficacy of CAR-T cell therapy.
399.50 399.5 USD
AffiAB® Anti-Glypican-3 Antibody
CAT# AFG-BMG-3117
Size: 100 µg
138.25 138.25 USD
AffiAB® Anti-CD22 Antibody
CAT# AFG-BMG-3101
Size: 100 µg
138.25 138.25 USD
AffiAB® Anti Human GPC3 Polyclonal Antibody
CAT# AFG-BMG-1170
Size: 100 µl
527.28 527.28 USD
AffiAB® Anti-HER2 Antibody
CAT# AFG-BMG-1003
Size: 100 µl
138.25 138.25 USD
AffiAB® Anti-HER2 (Ab-1248) Antibody
CAT# AFG-BMG-0736
Size: 100 µg
237.24 237.24 USD
AffiAB® Anti-HER2 (Ab-1221/1222) Antibody
CAT# AFG-BMG-0735
Size: 100 µg
237.24 237.24 USD
AffiAB® Anti-HER2 (Ab-877) Antibody
CAT# AFG-BMG-0734
Size: 100 µg
237.24 237.24 USD
AffiAB® Anti-HER2 (Phospho-Tyr1248) Antibody
CAT# AFG-BMG-0423
Size: 100 µg
237.24 237.24 USD
237.24 237.24 USD
AffiAB® Anti-HER2 (Phospho-Tyr877) Antibody
CAT# AFG-BMG-0419
Size: 100 µg
237.24 237.24 USD
AffiAB® CD22 Antibody
CAT# AFG-BMG-0241
Size: 0.1 mL
For Price Contact info@affigen.com 0.0 USD
AffiAB® Glypican-3 Antibody
CAT# AFG-BMG-0186
Size: 0.1 mL
156.97 156.97 USD
AffiAB® CD123 Antibody
CAT# AFG-BMG-0167
Size: 0.1 mL
131.03 131.03 USD
AffiAB® CD30 Antibody
CAT# AFG-BMG-0145
Size: 0.1 mL
70.52 70.52 USD
AffiAB® Her2/Neu Antibody
CAT# AFG-BMG-0065
Size: 0.1 mL
87.81 87.81 USD
271.25 271.25 USD
AffiAB®​​ MSLN Rabbit Polyclonal Antibody
CAT# AFG-BTL-08446
Size: 100 uL
271.25 271.25 USD
271.25 271.25 USD
271.25 271.25 USD
271.25 271.25 USD
271.25 271.25 USD
AffiAB®​​ HER2 Monoclonal Antibody (3C9)
CAT# AFG-BTL-05898
Size: 100 uL
271.25 271.25 USD
AffiAB®​​ HER2 Monoclonal Antibody (11H9)
CAT# AFG-BTL-05897
Size: 100 uL
271.25 271.25 USD
AffiAB®​​ GPC39 Polyclonal Antibody
CAT# AFG-BTL-05509
Size: 100 uL
271.25 271.25 USD
AffiAB®​​ Glypican-3 Polyclonal Antibody
CAT# AFG-BTL-05434
Size: 100 uL
271.25 271.25 USD
AffiAB®​​ CD33 Polyclonal Antibody
CAT# AFG-BTL-02048
Size: 100 uL
271.25 271.25 USD
AffiAB®​​ CD33 Monoclonal Antibody
CAT# AFG-BTL-02047
Size:
295.00 295.0 USD
AffiAB®​​ CD30-L Polyclonal Antibody
CAT# AFG-BTL-02033
Size: 100 uL
271.25 271.25 USD
AffiAB®​​ CD22 Polyclonal Antibody
CAT# AFG-BTL-01977
Size: 100 uL
271.25 271.25 USD
AffiAB®​​ CD123 Polyclonal Antibody
CAT# AFG-BTL-01905
Size: 100 uL
271.25 271.25 USD
AffiAB®​​ CCD33 Rabbit Polyclonal Antibody
CAT# AFG-BTL-01814
Size: 100 uL
271.25 271.25 USD
AffiAB®​ BCMA (mouse) Antibody [Vicky-2]
CAT# AFG-KMY-0062
Size: 100 μg
601.85 601.85 USD
366.25 366.25 USD
366.25 366.25 USD
390.00 390.0 USD
437.50 437.5 USD
342.50 342.5 USD
AffiAB®​ Anti-Human CD33, Unlabeled
CAT# AFG-APD-3869
Size: 100 ug
342.50 342.5 USD
AffiAB®​ Anti-Human CD33-PE-Cy5-conjugate
CAT# AFG-APD-3868
Size: 100 tests
295.00 295.0 USD
AffiAB®​ Anti-Human CD33-PE conjugate
CAT# AFG-APD-3867
Size: 100 tests
295.00 295.0 USD
AffiAB®​ Anti-Human CD33-FITC conjugate
CAT# AFG-APD-3866
Size: 100 tests
295.00 295.0 USD
AffiAB®​ Anti-Human CD19-PE conjugate
CAT# AFG-APD-3817
Size: 100 tests
295.00 295.0 USD
AffiAB®​ Anti-Human CD19 FITC/CD2 PE
CAT# AFG-APD-3813
Size: 50 tests
485.00 485.0 USD
AffiAB®​ Anti-Human CD5 FITC/CD19 PE
CAT# AFG-APD-3746
Size: 50 tests
485.00 485.0 USD
AffiAB®​ Anti-Human CD3 FITC/CD19 PE/CD45 PE-Cy5
CAT# AFG-APD-3733
Size: 50 tests
485.00 485.0 USD
AffiAB®​ Anti-Human CD3 FITC/CD19 PE
CAT# AFG-APD-3727
Size: 50 tests
485.00 485.0 USD
AffiAB®​ Anti-Human CD2 FITC/CD19-PE
CAT# AFG-APD-3720
Size: 50 tests
485.00 485.0 USD
295.00 295.0 USD
427.05 427.05 USD
AffiAB®​ Anti-HER2 (Phospho-Tyr1248) Antibody
CAT# AFG-QDB-1589
Size: 100 μ L
357.70 357.7 USD
357.70 357.7 USD
AffiAB®​ Anti-HER2 (Phospho-Tyr877) Antibody
CAT# AFG-QDB-1585
Size: 100 μ L
357.70 357.7 USD
432.75 432.75 USD
AffiAB®​ Anti-Her2/Neu Antibody
CAT# AFG-QDB-1456
Size: 100 μ L
241.80 241.8 USD
624.55 624.5500000000001 USD
624.55 624.5500000000001 USD
420.00 420.0 USD
624.55 624.5500000000001 USD
420.00 420.0 USD
624.55 624.5500000000001 USD