CD33 Antibodies

Gene Name: CD33 (Cluster of Differentiation 33)

Function: CD33 is a cell surface protein belonging to the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It is primarily expressed on cells of myeloid lineage, including myeloid progenitor cells, monocytes, macrophages, dendritic cells, and granulocytes. CD33 is involved in regulating myeloid cell development, activation, and function.

Immune Regulation: CD33 plays a role in modulating immune responses, particularly in the context of myeloid cell activation and inflammation. It is involved in inhibitory signaling pathways that regulate myeloid cell activation and cytokine production. CD33 can act as an inhibitory receptor that dampens immune responses and prevents excessive inflammation.

Apoptosis: While CD33 itself does not directly induce apoptosis, dysregulation of CD33 signaling can affect myeloid cell survival and contribute to the pathogenesis of certain myeloid malignancies. Aberrant CD33 expression or function has been observed in acute myeloid leukemia (AML) and other myeloid disorders, suggesting a potential role in apoptosis regulation in these diseases.

Research Implications: Understanding the functions of CD33 is important for elucidating its roles in myeloid cell biology and immune regulation. Research on CD33 signaling pathways may have implications for the development of therapies targeting myeloid-related diseases and inflammatory disorders.

Clinical Relevance: CD33 has emerged as a therapeutic target for the treatment of acute myeloid leukemia (AML). Monoclonal antibodies targeting CD33, such as gemtuzumab ozogamicin, have been developed for the treatment of AML. These antibodies deliver cytotoxic agents directly to CD33-expressing leukemia cells, leading to cell death. Additionally, CD33-directed CAR-T cell therapies are being investigated for the treatment of CD33-positive AML.

AffiAB®​​ CD33 Polyclonal Antibody
CAT# AFG-BTL-02048
Size: 100 uL
271.25 271.25 USD
AffiAB®​​ CD33 Monoclonal Antibody
CAT# AFG-BTL-02047
Size:
295.00 295.0 USD
AffiAB®​​ CCD33 Rabbit Polyclonal Antibody
CAT# AFG-BTL-01814
Size: 100 uL
271.25 271.25 USD
AffiAB®​ Anti-Human CD33, Unlabeled
CAT# AFG-APD-3869
Size: 100 ug
342.50 342.5 USD
AffiAB®​ Anti-Human CD33-PE-Cy5-conjugate
CAT# AFG-APD-3868
Size: 100 tests
295.00 295.0 USD
AffiAB®​ Anti-Human CD33-PE conjugate
CAT# AFG-APD-3867
Size: 100 tests
295.00 295.0 USD
AffiAB®​ Anti-Human CD33-FITC conjugate
CAT# AFG-APD-3866
Size: 100 tests
295.00 295.0 USD
399.50 399.5 USD
286.45 286.45 USD
293.10 293.1 USD
AffiAB® Anti-CD33 Antibody
CAT# AFG-BRB-08059
Size: 0.1mg
436.55 436.55 USD
AffiAB®​ Anti-Hu CD335 Purified [9E2]
CAT# AFG-XBO-1244
Size: 25 tests
143.00 143.0 USD
AffiAB®​ Anti-Hu CD335 PE [9E2]
CAT# AFG-XBO-1243
Size: 25 tests
219.00 219.0 USD
AffiAB®​ Anti-Hu CD334 Purified [4FR6D3]
CAT# AFG-XBO-1242
Size: 25 tests
143.00 143.0 USD
AffiAB®​ Anti-Hu CD334 PE [4FR6D3]
CAT# AFG-XBO-1241
Size: 25 tests
114.50 114.5 USD
133.50 133.5 USD
AffiAB®​ Anti-Hu CD33 Purified [WM53]
CAT# AFG-XBO-1239
Size: 25 tests
133.50 133.5 USD
AffiAB®​ Anti-Hu CD33 Purified [HIM3-4]
CAT# AFG-XBO-1238
Size: 25 tests
143.00 143.0 USD
AffiAB®​ Anti-Hu CD33 PerCP-Cy5.5 [WM53]
CAT# AFG-XBO-1237
Size: 25 tests
152.50 152.5 USD
AffiAB®​ Anti-Hu CD33 PerCP [WM53]
CAT# AFG-XBO-1236
Size: 25 tests
114.50 114.5 USD
AffiAB®​ Anti-Hu CD33 PE-Cy7 [WM53]
CAT# AFG-XBO-1235
Size: 25 tests
247.50 247.5 USD
AffiAB®​ Anti-Hu CD33 PE-Cy5 [WM53]
CAT# AFG-XBO-1234
Size: 25 tests
114.50 114.5 USD
AffiAB®​ Anti-Hu CD33 PE [WM53]
CAT# AFG-XBO-1233
Size: 25 tests
114.50 114.5 USD
AffiAB®​ Anti-Hu CD33 Pacific Blue [WM53]
CAT# AFG-XBO-1232
Size: 25 tests
219.00 219.0 USD
AffiAB®​ Anti-Hu CD33 FITC [WM53]
CAT# AFG-XBO-1231
Size: 25 tests
95.50 95.5 USD
AffiAB®​ Anti-Hu CD33 Biotin [HIM3-4]
CAT# AFG-XBO-1230
Size: 25 tests
181.00 181.0 USD
AffiAB®​ Anti-Hu CD33 APC-Cy7 [WM53]
CAT# AFG-XBO-1229
Size: 25 tests
128.75 128.75 USD
AffiAB®​ Anti-Hu CD33 APC [WM53]
CAT# AFG-XBO-1228
Size: 25 tests
114.50 114.5 USD
AffiAB®​ Anti-Hu CD33 Alexa Fluor 700 [WM53]
CAT# AFG-XBO-1227
Size: 25 tests
114.50 114.5 USD
AffiAB® Human CD33 Antibody (Biotin Conjugate)
CAT# AFG-SYP-2989
Size: 150 μg
309.25 309.25 USD
AffiAB® Rabbit Anti-CD33 Polyclonal Antibody
CAT# AFG-KMD-5335
Size: 100 μL
399.50 399.5 USD
AffiAB® Mouse anti-CD33 Antibody
CAT# AFG-DDA-9367
Size: 100 μL
284.05 284.05 USD
AffiAB® Mouse anti-CD33 Antibody
CAT# AFG-DDA-9366
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-CD339 Antibody
CAT# AFG-DDA-9149
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit Anti-CD337 Antibody
CAT# AFG-DDA-8894
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-CD33 Antibody
CAT# AFG-DDA-3203
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-CD33 Antibody
CAT# AFG-DDA-1370
Size: 100 μL
274.55 274.55 USD
AffiAB® Rabbit anti-CD335 Antibody
CAT# AFG-DDA-0434
Size: 100 μL
256.50 256.5 USD
AffiAB® Rabbit anti-CD335 Antibody
CAT# AFG-DDA-0110
Size: 100 μL
256.50 256.5 USD
AffiAB® CD33 Polyclonal Antibody
CAT# AFG-PAB-02296
Size: 100 µg
Conjugation: Unconjugated
267.00 267.0 USD
AffiAB® Rabbit anti-CD335 Antibody
CAT# AFG-YBP-1744
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-CD335 Antibody
CAT# AFG-YBP-1743
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-CD33 Antibody
CAT# AFG-YBP-1742
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-CD33 Antibody
CAT# AFG-YBP-1741
Size: 100 µL
457.00 457.0 USD
AffiAB® Anti-FGFR2/CD332 Antibody [A5-E10-G7]
CAT# AFG-HB-1459
Size: 100 μL
315.00 315.0 USD
AffiAB® Anti-FGFR2/CD332 Antibody [1-F1-E7]
CAT# AFG-HB-1458
Size: 100 μL
315.00 315.0 USD
AffiAB® Anti-FGFR2/CD332 Antibody
CAT# AFG-HB-1456
Size: 100 μL
283.50 283.5 USD
AffiAB® Anti-Hu CD33 PerCP-Cy5.5 [WM53]
CAT# AFG-EXB-2325
Size: 100 Tests
285.00 285.0 USD
AffiAB® Anti-Hu CD33 PE-Cy5 [WM53]
CAT# AFG-EXB-2269
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD33 PE-Cy7 [WM53]
CAT# AFG-EXB-2210
Size: 100 Tests
237.00 237.0 USD
AffiAB® Anti-Hu CD33 APC-Cy7 [WM53]
CAT# AFG-EXB-2119
Size: 100 Tests
237.00 237.0 USD
AffiAB® Anti-Hu CD33 PerCP [WM53]
CAT# AFG-EXB-2057
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD33 Pacific Blue [WM53]
CAT# AFG-EXB-2005
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD33 Alexa Fluor 700 [WM53]
CAT# AFG-EXB-1928
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD335 PE [9E2]
CAT# AFG-EXB-1705
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD33 PE [WM53]
CAT# AFG-EXB-1575
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD334 PE [4FR6D3]
CAT# AFG-EXB-1537
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD33 FITC [WM53]
CAT# AFG-EXB-1297
Size: 0.1 mg
171.00 171.0 USD
AffiAB® Anti-Hu CD33 Biotin [HIM3-4]
CAT# AFG-EXB-1076
Size: 0.1 mg
171.00 171.0 USD
AffiAB® Anti-Hu CD33 APC [WM53]
CAT# AFG-EXB-0947
Size: 0.1 mg
209.00 209.0 USD
123.00 123.0 USD
AffiAB® Anti-Hu CD335 Purified [9E2]
CAT# AFG-EXB-0629
Size: 0.1 mg
133.00 133.0 USD
AffiAB® Anti-Hu CD33 Purified [WM53]
CAT# AFG-EXB-0471
Size: 0.1 mg
123.00 123.0 USD
AffiAB® Anti-Hu CD334 Purified [4FR6D3]
CAT# AFG-EXB-0420
Size: 0.1 mg
133.00 133.0 USD
AffiAB® Anti-Hu CD33 Purified [HIM3-4]
CAT# AFG-EXB-0256
Size: 0.1 mg
133.00 133.0 USD
520.00 520.0 USD
AffiAB® PerCP/Cyanine5.5 Anti-Human CD33 Antibody
CAT# AFG-DDF-2237
Size: 100 Tests
600.00 600.0 USD
AffiAB® PE/Cyanine7 Anti-Human CD33 Antibody
CAT# AFG-DDF-2004
Size: 100 Tests
600.00 600.0 USD
AffiAB® PE/Cyanine5 Anti-Mouse CD335 Antibody
CAT# AFG-DDF-1746
Size: 100 μg
600.00 600.0 USD
AffiAB® PE/Cyanine5 Anti-Mouse CD335 Antibody
CAT# AFG-DDF-1745
Size: 100 Tests
697.50 697.5 USD
AffiAB® PE Anti-Mouse CD335 Antibody
CAT# AFG-DDF-1533
Size: 100 μg
645.00 645.0 USD
AffiAB® PE Anti-Mouse CD335 Antibody
CAT# AFG-DDF-1532
Size: 100 Tests
555.00 555.0 USD
AffiAB® PE Anti-Human CD33 Antibody
CAT# AFG-DDF-1419
Size: 100 Tests
487.50 487.5 USD
AffiAB® FITC Anti-Mouse CD335 Antibody
CAT# AFG-DDF-1238
Size: 100 μg
555.00 555.0 USD
AffiAB® FITC Anti-Mouse CD335 Antibody
CAT# AFG-DDF-1237
Size: 100 Tests
555.00 555.0 USD
AffiAB® FITC Anti-Human CD33 Antibody
CAT# AFG-DDF-1147
Size: 100 Tests
487.50 487.5 USD
AffiAB® APC Anti-Mouse CD335 Antibody
CAT# AFG-DDF-0888
Size: 100 μg
645.00 645.0 USD
AffiAB® APC Anti-Mouse CD335 Antibody
CAT# AFG-DDF-0887
Size: 100 Tests
600.00 600.0 USD
AffiAB® APC Anti-Human CD33 Antibody
CAT# AFG-DDF-0777
Size: 100 Tests
487.50 487.5 USD
625.00 625.0 USD
760.00 760.0 USD
760.00 760.0 USD
730.00 730.0 USD
760.00 760.0 USD
AffiAB® AF488 Anti-Human CD33 Antibody
CAT# AFG-DDF-0124
Size: 100 Tests
600.00 600.0 USD
AffiAB® Human CD33C Antibody : APC
CAT# AFG-IVA-14473
Size: 25 Tests
Terminal: N/A
170.05 170.05 USD
AffiAB® Human CD33 Antibody : SPRD
CAT# AFG-IVA-14472
Size: 100 Tests
Terminal: N/A
331.55 331.55 USD
AffiAB® Human CD33 Antibody : PE/Cy5.5
CAT# AFG-IVA-14471
Size: 100 Tests
Terminal: N/A
341.05 341.05 USD
AffiAB® Human CD33 Antibody : PE
CAT# AFG-IVA-14470
Size: 100 Tests
Terminal: N/A
284.05 284.05 USD
AffiAB® Human CD33 Antibody : LE/AF
CAT# AFG-IVA-14469
Size: 0.5 mg
Terminal: N/A
445.55 445.55 USD
AffiAB® Human CD33 Antibody : FITC
CAT# AFG-IVA-14468
Size: 100 Tests
Terminal: N/A
227.05 227.05 USD
AffiAB® Human CD33 Antibody : APC
CAT# AFG-IVA-14467
Size: 100 Tests
Terminal: N/A
341.05 341.05 USD
AffiAB® Human CD33 Antibody
CAT# AFG-IVA-14466
Size: 0.1 mg
Terminal: N/A
122.55 122.55 USD
AffiAB® Hamster ANTI CD339 Antibody
CAT# AFG-IVA-12962
Size: 0.1 mg
Terminal: N/A
293.55 293.55 USD
AffiAB® CD33 Detection Antibody
CAT# AFG-IVA-05423
Size: 50 µg
Terminal: N/A
417.05 417.05 USD