CD30 Antibodies

Gene Name: CD30 (Cluster of Differentiation 30)

Function: CD30 is a cell surface protein belonging to the tumor necrosis factor receptor (TNFR) superfamily. It is primarily expressed on activated T cells, B cells, and certain types of lymphoma cells. CD30 plays a role in regulating cell survival, proliferation, and apoptosis.

Immune Regulation: CD30 is involved in modulating immune responses, particularly in the context of T cell activation and differentiation. It is expressed on activated T cells and can promote T cell proliferation and cytokine production upon engagement with its ligand, CD30L (CD153). CD30 signaling may also play a role in regulating B cell activation and antibody production.

Apoptosis: In certain circumstances, CD30 signaling can induce apoptosis (programmed cell death) in activated lymphocytes, including both T cells and B cells. This apoptotic function of CD30 is thought to contribute to the regulation of immune responses and the resolution of immune reactions.

Research Implications: Understanding the functions of CD30 is important for elucidating its roles in immune regulation and lymphocyte biology. Research on CD30 signaling pathways may have implications for the development of therapies targeting immune-related diseases and lymphoid malignancies.

Clinical Relevance: CD30 has emerged as a therapeutic target for the treatment of certain lymphomas and autoimmune diseases. Monoclonal antibodies targeting CD30, such as brentuximab vedotin, have been developed for the treatment of Hodgkin lymphoma and anaplastic large cell lymphoma (ALCL). These antibodies deliver cytotoxic agents directly to CD30-expressing cancer cells, leading to cell death. Additionally, CD30-directed CAR-T cell therapies are being investigated for the treatment of CD30-positive lymphomas.

AffiAB® CD30 Antibody
CAT# AFG-BMG-0145
Size: 0.1 mL
70.52 70.52 USD
AffiAB®​​ CD30-L Polyclonal Antibody
CAT# AFG-BTL-02033
Size: 100 uL
271.25 271.25 USD
624.55 624.5500000000001 USD
624.55 624.5500000000001 USD
AffiAB®​ CD30 (Ki-1/779), 1mg/mL Antibody
CAT# AFG-BTM-04465
Size: 50 μL
624.55 624.5500000000001 USD
AffiAB®​ CD30 (Ki-1/779), 0.2mg/mL Antibody
CAT# AFG-BTM-04464
Size: 100 μL
420.00 420.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
624.55 624.5500000000001 USD
AffiAB®​ CD30 (CD30/412), 1mg/mL Antibody
CAT# AFG-BTM-02353
Size: 50 μL
624.55 624.5500000000001 USD
AffiAB®​ CD30 (CD30/412), 0.2mg/mL Antibody
CAT# AFG-BTM-02352
Size: 100 μL
420.00 420.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
506.85 506.85 USD
AffiAB®​ Anti-Hu CD30 Purified [MEM-268]
CAT# AFG-XBO-1147
Size: 0.1 mg
143.00 143.0 USD
AffiAB®​ Anti-Hu CD30 Purified [Ber-H8]
CAT# AFG-XBO-1146
Size: 0.1 mg
133.50 133.5 USD
AffiAB®​ Anti-Hu CD30 PE [MEM-268]
CAT# AFG-XBO-1145
Size: 0.1 mg
114.50 114.5 USD
AffiAB®​ Anti-Hu CD30 PE [Ber-H8]
CAT# AFG-XBO-1144
Size: 0.1 mg
114.50 114.5 USD
AffiAB®​ Anti-Hu CD30 FITC [MEM-268]
CAT# AFG-XBO-1143
Size: 0.1 mg
95.50 95.5 USD
AffiAB®​ Anti-Hu CD30 FITC [Ber-H8]
CAT# AFG-XBO-1142
Size: 0.1 mg
95.50 95.5 USD
AffiAB®​ Anti-Hu CD30 APC [MEM-268]
CAT# AFG-XBO-1141
Size: 0.1 mg
114.50 114.5 USD
219.00 219.0 USD
114.50 114.5 USD
399.50 399.5 USD
AffiAB® Rabbit anti-CD30 Antibody
CAT# AFG-DDA-0857
Size: 100 μL
256.50 256.5 USD
AffiAB® Rabbit anti-CD30 Antibody
CAT# AFG-YBP-1714
Size: 100 µL
457.00 457.0 USD
AffiAB® Anti-Hu CD30 Alexa Fluor 700 [MEM-268]
CAT# AFG-EXB-1915
Size: 0.1 mg
209.00 209.0 USD
AffiAB® Anti-Hu CD30 Alexa Fluor 647 [MEM-268]
CAT# AFG-EXB-1854
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD30 PE [MEM-268]
CAT# AFG-EXB-1495
Size: 100 Tests
209.00 209.0 USD