CD22 Antibodies

Gene Name: CD22 (Cluster of Differentiation 22)

Function: CD22 is a cell surface protein belonging to the immunoglobulin superfamily. It is primarily expressed on B cells and plays a role in regulating B cell activation and signaling. CD22 acts as an inhibitory receptor that modulates B cell receptor (BCR) signaling and helps to prevent excessive activation of B cells.

Immune Regulation: CD22 is involved in regulating B cell responses to antigens and maintaining immune tolerance. By dampening BCR signaling, CD22 helps to prevent the activation of autoreactive B cells and the production of autoantibodies, thereby contributing to immune homeostasis and preventing autoimmune diseases.

Apoptosis: While CD22 itself does not directly induce apoptosis, dysregulation of CD22 signaling can affect B cell survival and contribute to the pathogenesis of certain B cell malignancies. Aberrant CD22 expression or function has been observed in B cell lymphomas and leukemias, highlighting its potential role in apoptosis regulation in these diseases.

Research Implications: Understanding the functions of CD22 is important for elucidating the mechanisms underlying B cell regulation and immune tolerance. Research on CD22 may have implications for the development of therapies targeting B cell-related diseases, including autoimmune disorders and B cell malignancies.

Clinical Relevance: CD22 has emerged as a therapeutic target for immunotherapy in B cell malignancies. Monoclonal antibodies targeting CD22, such as inotuzumab ozogamicin, have been developed for the treatment of B cell acute lymphoblastic leukemia (B-ALL) and other CD22-positive malignancies. Additionally, CD22-directed CAR-T cell therapies are being investigated as a promising approach for treating B-ALL and other CD22-positive hematological malignancies.

AffiAB® Anti-CD22 Antibody
CAT# AFG-BMG-3101
Size: 100 µg
138.25 138.25 USD
AffiAB® CD22 Antibody
CAT# AFG-BMG-0241
Size: 0.1 mL
For Price Contact info@affigen.com 0.0 USD
271.25 271.25 USD
AffiAB®​​ CD22 Polyclonal Antibody
CAT# AFG-BTL-01977
Size: 100 uL
271.25 271.25 USD
624.55 624.5500000000001 USD
420.00 420.0 USD
624.55 624.5500000000001 USD
420.00 420.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
624.55 624.5500000000001 USD
420.00 420.0 USD
AffiAB®​ CD22 (Myg13), 1mg/mL Antibody
CAT# AFG-BTM-06016
Size: 50 μL
624.55 624.5500000000001 USD
AffiAB®​ CD22 (Myg13), 0.2mg/mL Antibody
CAT# AFG-BTM-06015
Size: 100 μL
420.00 420.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
AffiAB®​ CD22 (FR10B4), 1mg/mL Antibody
CAT# AFG-BTM-02063
Size: 50 μL
624.55 624.5500000000001 USD
AffiAB®​ CD22 (FR10B4), 0.2mg/mL Antibody
CAT# AFG-BTM-02062
Size: 100 μL
420.00 420.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
380.00 380.0 USD
506.85 506.85 USD
506.85 506.85 USD
AffiAB® Anti-CD22 / BL-CAM Monoclonal Antibody
CAT# AFG-BRB-04025
Size: 100 μg
454.60 454.6 USD
AffiAB® Rabbit Anti-CD22 Polyclonal Antibody
CAT# AFG-KMD-5277
Size: 100 μL
399.50 399.5 USD
AffiAB® Mouse anti-CD22 Antibody
CAT# AFG-DDA-9357
Size: 100 μL
284.05 284.05 USD
AffiAB® Mouse anti-CD22 Antibody
CAT# AFG-DDA-9356
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-CD22 Antibody
CAT# AFG-DDA-1419
Size: 100 μL
274.55 274.55 USD
AffiAB® Phospho-CD22 - Tyr807 Polyclonal Antibody
CAT# AFG-PAB-02272
Size: 100ul
Conjugation: Unconjugated
460.00 460.0 USD
AffiAB® CD22 - Ab-807 Polyclonal Antibody
CAT# AFG-PAB-02271
Size: 100ul
Conjugation: Unconjugated
397.00 397.0 USD
AffiAB® Phospho-CD22 - Y807 Polyclonal Antibody
CAT# AFG-PAB-02270
Size: 100 µg
Conjugation: Unconjugated
267.00 267.0 USD
AffiAB® CD22 Polyclonal Antibody
CAT# AFG-PAB-02269
Size: 100 µg
Conjugation: Unconjugated
267.00 267.0 USD
AffiAB® Rabbit anti-CD22 Antibody
CAT# AFG-YBP-1645
Size: 100 µL
457.00 457.0 USD
AffiAB® Anti-Hu CD22 PerCP-Cy5.5 [S-HCL-1]
CAT# AFG-EXB-2286
Size: 100 Tests
285.00 285.0 USD
AffiAB® Anti-Hu CD22 PE-Cy7 [IS7]
CAT# AFG-EXB-2187
Size: 100 Tests
237.00 237.0 USD
AffiAB® Anti-Hu CD22 PE-Cy7 [S-HCL-1]
CAT# AFG-EXB-2159
Size: 100 Tests
237.00 237.0 USD
AffiAB® Anti-Hu CD22 Pacific Blue [IS7]
CAT# AFG-EXB-1993
Size: 0.1 mg
209.00 209.0 USD
AffiAB® Anti-Hu CD22 Pacific Blue& 153 [S-HCL-1]
CAT# AFG-EXB-1952
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD22 Alexa Fluor 700 [IS7]
CAT# AFG-EXB-1919
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD22 Alexa Fluor 700 [S-HCL-1]
CAT# AFG-EXB-1887
Size: 0.1 mg
209.00 209.0 USD
AffiAB® Anti-Hu CD22 PE [IS7]
CAT# AFG-EXB-1507
Size: 0.1 mg
209.00 209.0 USD
AffiAB® Anti-Hu CD22 PE [MEM-01]
CAT# AFG-EXB-1441
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD22 PE [S-HCL-1]
CAT# AFG-EXB-1397
Size: 0.1 mg
209.00 209.0 USD
AffiAB® Anti-Hu CD22 FITC [IS7]
CAT# AFG-EXB-1239
Size: 100 Tests
171.00 171.0 USD
AffiAB® Anti-Hu CD22 FITC [S-HCL-1]
CAT# AFG-EXB-1145
Size: 0.1 mg
171.00 171.0 USD
AffiAB® Anti-Hu CD22 Biotin [MEM-01]
CAT# AFG-EXB-1057
Size: 0.1 mg
171.00 171.0 USD
AffiAB® Anti-Hu CD22 APC [IS7]
CAT# AFG-EXB-0890
Size: 100 Tests
209.00 209.0 USD
AffiAB® Anti-Hu CD22 APC [S-HCL-1]
CAT# AFG-EXB-0816
Size: 0.1 mg
209.00 209.0 USD
AffiAB® Anti-Hu CD22 Purified [MEM-01]
CAT# AFG-EXB-0183
Size: 0.1 mg
123.00 123.0 USD
AffiAB® Anti-Hu CD22 Purified [S-HCL-1]
CAT# AFG-EXB-0101
Size: 0.1 mg
123.00 123.0 USD
AffiAB® Anti-Hu CD22 Purified Azide Free [IS7]
CAT# AFG-EXB-0018
Size: 0.1 mg
123.00 123.0 USD
625.00 625.0 USD
AffiAB® PerCP/Cyanine5.5 Anti-Mouse CD22 Antibody
CAT# AFG-DDF-2287
Size: 100 μg
600.00 600.0 USD
AffiAB® PerCP/Cyanine5.5 Anti-Mouse CD22 Antibody
CAT# AFG-DDF-2286
Size: 100 Tests
547.50 547.5 USD
AffiAB® PerCP/Cyanine5.5 Anti-Human CD22 Antibody
CAT# AFG-DDF-2229
Size: 100 Tests
600.00 600.0 USD
AffiAB® PE/Cyanine7 Anti-Mouse CD22 Antibody
CAT# AFG-DDF-2064
Size: 100 μg
600.00 600.0 USD
AffiAB® PE/Cyanine7 Anti-Mouse CD22 Antibody
CAT# AFG-DDF-2063
Size: 100 Tests
547.50 547.5 USD
AffiAB® PE/Cyanine5.5 Anti-Mouse CD22 Antibody
CAT# AFG-DDF-1888
Size: 100 μg
600.00 600.0 USD
AffiAB® PE/Cyanine5.5 Anti-Mouse CD22 Antibody
CAT# AFG-DDF-1887
Size: 100 Tests
547.50 547.5 USD
AffiAB® PE/Cyanine5 Anti-Mouse CD22 Antibody
CAT# AFG-DDF-1736
Size: 100 μg
600.00 600.0 USD
AffiAB® PE/Cyanine5 Anti-Mouse CD22 Antibody
CAT# AFG-DDF-1735
Size: 100 Tests
547.50 547.5 USD
AffiAB® PE/Cyanine5 Anti-Human CD22 Antibody
CAT# AFG-DDF-1670
Size: 100 Tests
600.00 600.0 USD
AffiAB® PE Anti-Human CD22 Antibody
CAT# AFG-DDF-1405
Size: 100 Tests
487.50 487.5 USD
AffiAB® FITC Anti-Human CD22 Antibody
CAT# AFG-DDF-1134
Size: 100 Tests
487.50 487.5 USD
AffiAB® Biotin Anti-Mouse CD22 Antibody
CAT# AFG-DDF-1064
Size: 100 μg
555.00 555.0 USD
AffiAB® APC Anti-Mouse CD22 Antibody
CAT# AFG-DDF-0866
Size: 100 μg
555.00 555.0 USD
AffiAB® APC Anti-Mouse CD22 Antibody
CAT# AFG-DDF-0865
Size: 100 Tests
420.00 420.0 USD
AffiAB® APC Anti-Human CD22 Antibody
CAT# AFG-DDF-0764
Size: 100 Tests
487.50 487.5 USD
400.00 400.0 USD
400.00 400.0 USD
400.00 400.0 USD