MYH Antibodies

MYH antibodies are specific reagents used to detect and study different myosin heavy chain isoforms in various tissues. These antibodies are crucial for research in muscle biology, muscle-related diseases, and myopathies. MYH antibodies target specific isoforms of myosin heavy chains, providing detailed insights into their role in muscle contraction, cellular movement, and tissue development.

Applications of MYH Antibodies

  • Western Blotting (WB): MYH antibodies are widely used in Western blot assays to detect specific myosin heavy chain isoforms in cell or tissue lysates. This is useful for studying changes in myosin expression in muscle development, differentiation, or muscle diseases such as cardiomyopathies and muscular dystrophies.
  • Immunohistochemistry (IHC): MYH antibodies are utilized in IHC to localize myosin heavy chain proteins in tissue sections. This application is essential in examining the expression patterns of MYH isoforms in skeletal, cardiac, or smooth muscle tissues and studying structural changes in muscles during disease.
  • Immunoprecipitation (IP): MYH antibodies are employed in immunoprecipitation experiments to isolate specific myosin heavy chain isoforms from cell or tissue extracts. This method helps in investigating the interactions between myosin and other proteins involved in muscle contraction, cytoskeletal dynamics, and intracellular transport.
  • ELISA: MYH antibodies can be used in ELISA assays to quantify specific myosin isoforms in serum or tissue samples. This application is beneficial for diagnostic or research purposes, especially in tracking disease progression in conditions like hypertrophic cardiomyopathy or muscular dystrophy.

Key MYH Isoforms Targeted by Antibodies

  • MYH7 (Myosin Heavy Chain 7): This isoform is primarily expressed in cardiac muscle and slow-twitch skeletal muscle fibers. MYH7 mutations are commonly associated with hypertrophic cardiomyopathy (HCM) and other muscle-related diseases. Anti-MYH7 antibodies are essential for studying cardiac muscle function, cardiomyopathies, and muscle fiber composition.
  • MYH9 (Myosin Heavy Chain 9): MYH9 is expressed in non-muscle cells and plays a role in cellular processes such as cytokinesis, intracellular transport, and maintaining cell shape. Mutations in MYH9 are linked to MYH9-related disorders, which include nephropathy, hearing loss, and platelet abnormalities. Anti-MYH9 antibodies are crucial for studying these diseases and understanding the role of non-muscle myosin in cell biology.

MYH antibodies are indispensable tools for studying the myosin heavy chain family, particularly in research on muscle contraction, myopathies, and cardiomyopathies. They enable researchers to detect, quantify, and localize specific MYH isoforms, providing insights into their roles in muscle biology and disease.


AffiAB® MYH9 Polyclonal Antibody
CAT# AFG-PAB-09730
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® MYH7B Polyclonal Antibody
CAT# AFG-PAB-09729
Size: 100 µg
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® MYH7 Polyclonal Antibody
CAT# AFG-PAB-09728
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® MYH6/MYH7 Polyclonal Antibody
CAT# AFG-PAB-09727
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® MYH6 Polyclonal Antibody
CAT# AFG-PAB-09726
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® MYH4 Polyclonal Antibody
CAT# AFG-PAB-09725
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® MYH3 Polyclonal Antibody
CAT# AFG-PAB-09724
Size: 100 µg
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® MYH2 Polyclonal Antibody
CAT# AFG-PAB-09723
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® MYH15 Polyclonal Antibody
CAT# AFG-PAB-09722
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® MYH14 Polyclonal Antibody
CAT# AFG-PAB-09721
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® MYH11 Polyclonal Antibody
CAT# AFG-PAB-09720
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® MYH10 Polyclonal Antibody
CAT# AFG-PAB-09719
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® MYH1/MYH2/MYH3/MYH4/MYH6/MYH7/MYH8 Polyclonal Antibody
CAT# AFG-PAB-09718
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® MYH1 Polyclonal Antibody
CAT# AFG-PAB-09717
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® Anti-MYH7B Antibody [JE54-44]
CAT# AFG-HB-2588
Size: 100 μL
496.50 496.5 USD
AffiAB® MYH1 Rabbit Polyclonal Antibody
CAT# AFG-EKA-11486
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH9 Rabbit Polyclonal Antibody
CAT# AFG-EKA-11425
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH11 Rabbit Polyclonal Antibody
CAT# AFG-EKA-10425
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH8 Rabbit Polyclonal Antibody
CAT# AFG-EKA-09351
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH3 Rabbit Polyclonal Antibody
CAT# AFG-EKA-09350
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH2 Rabbit Polyclonal Antibody
CAT# AFG-EKA-09349
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH6 Rabbit Polyclonal Antibody
CAT# AFG-EKA-08374
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH6/MYH7 Rabbit Polyclonal Antibody
CAT# AFG-EKA-08316
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH15 Rabbit Polyclonal Antibody
CAT# AFG-EKA-04787
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH-pan Rabbit Polyclonal Antibody
CAT# AFG-EKA-03662
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH14 Rabbit Polyclonal Antibody
CAT# AFG-EKA-02380
Size: 100 µL
246.00 246.0 USD
AffiAB® MYH Rabbit Polyclonal Antibody
CAT# AFG-EKA-02379
Size: 100 µL
246.00 246.0 USD