AffiAB® Anti-MYH7B Antibody [JE54-44]
Myosin-7B also known as myosin, heavy chain 7B is a protein that in humans is encoded by the MYH7B gene.MYH7B is a slow-twitch myosin.The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: A7E2Y1 Human; SwissProt: A2AQP0 Mouse
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE54-44
KO/KD
N/A
Species reactivity
Rat, Human, Mouse
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human MYH7B aa 1, 710-1, 983 / 1, 983.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB:1:500-1:1, 000
Molecular Weight
226 kDa
Subcellular location
Membrane.
Positive control
Rat skeletal muscle tissue lysate, rat heart tissue lysate.