Lymphocyte Signaling Antibodies

Lymphocyte signaling antibodies are specialized antibodies designed to target and detect proteins involved in the signaling pathways of lymphocytes, including T cells, B cells, and natural killer (NK) cells. These proteins are essential for the activation, differentiation, and regulation of immune responses.

Content: Lymphocyte signaling antibodies can target a broad range of proteins that participate in various signaling pathways, including:

  • Receptors and Co-receptors: Such as the T cell receptor (TCR), B cell receptor (BCR), CD3, CD4, CD8, CD19, and CD28. These molecules are essential for antigen recognition and the initiation of downstream signaling cascades. Antibodies against these receptors help in studying lymphocyte activation and response to antigens.
  • Transcription Factors: Such as NF-κB, NFAT, STATs, and AP-1, which play a key role in regulating gene expression following lymphocyte activation. Antibodies against these transcription factors are used to study their activation, nuclear translocation, and impact on gene regulation in immune responses.

Applications: Lymphocyte signaling antibodies are widely used in various research and clinical applications, including:

  • Flow Cytometry: To analyze the expression and activation of surface and intracellular signaling proteins in lymphocytes. This is particularly useful for immunophenotyping, studying cell activation, and monitoring immune responses. For example, antibodies against CD3, CD4, and CD8 can identify T cell subpopulations, while phospho-specific antibodies can assess kinase activation states.
  • Western Blotting (WB): To detect and quantify the expression and phosphorylation of signaling proteins, providing insights into the activation and regulation of signaling pathways. This technique is valuable for studying receptor signaling, kinase activity, and downstream signaling events in lymphocytes.
  • Immunoprecipitation (IP) and Co-immunoprecipitation (Co-IP): To investigate protein-protein interactions within lymphocyte signaling pathways. This helps identify components of signaling complexes and elucidate how signals are transmitted within cells, such as interactions between TCR-associated proteins and downstream adaptors.

Lymphocyte signaling antibodies are indispensable for research in immunology, oncology, and infectious diseases. They provide critical insights into how lymphocytes detect and respond to antigens, how signaling pathways are regulated, and how dysregulation can lead to immune disorders, such as autoimmunity, immunodeficiency, and cancer. 

AffiAB® CD19 (Phospho Tyr500) Rabbit pAb
CAT# AFG-PNB-18246
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD247 Monoclonal Antibody (4B10)
CAT# AFG-PNB-18245
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD8A rabbit pAb
CAT# AFG-PNB-15435
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD14 rabbit pAb
CAT# AFG-PNB-15434
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD94 rabbit pAb
CAT# AFG-PNB-15433
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD86 rabbit pAb
CAT# AFG-PNB-15432
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® PBEF Polyclonal Antibody
CAT# AFG-PNB-15431
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD70 Polyclonal Antibody
CAT# AFG-PNB-15430
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD80 Polyclonal Antibody
CAT# AFG-PNB-15429
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD314 Polyclonal Antibody
CAT# AFG-PNB-15428
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD16 Polyclonal Antibody
CAT# AFG-PNB-15427
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® DC-LAMP Polyclonal Antibody
CAT# AFG-PNB-15426
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® ST6GAL1 Polyclonal Antibody
CAT# AFG-PNB-15425
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® MBL-C Polyclonal Antibody
CAT# AFG-PNB-15424
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD306 Polyclonal Antibody
CAT# AFG-PNB-15423
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD296 Polyclonal Antibody
CAT# AFG-PNB-15422
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD158e Polyclonal Antibody
CAT# AFG-PNB-15421
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® ICOS Polyclonal Antibody
CAT# AFG-PNB-15420
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD107b Polyclonal Antibody
CAT# AFG-PNB-15419
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD88 Polyclonal Antibody
CAT# AFG-PNB-15418
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD72 Polyclonal Antibody
CAT# AFG-PNB-15417
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD56 Polyclonal Antibody
CAT# AFG-PNB-15416
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD26 Polyclonal Antibody
CAT# AFG-PNB-15415
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® C7 Polyclonal Antibody
CAT# AFG-PNB-15414
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD269 Polyclonal Antibody
CAT# AFG-PNB-15413
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® Dectin-2 Polyclonal Antibody
CAT# AFG-PNB-15412
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® LAT Polyclonal Antibody
CAT# AFG-PNB-15411
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® Lambda 5 Polyclonal Antibody
CAT# AFG-PNB-15410
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD206 Polyclonal Antibody
CAT# AFG-PNB-15409
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD249 Polyclonal Antibody
CAT# AFG-PNB-15408
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD235a Polyclonal Antibody
CAT# AFG-PNB-15407
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD315 Polyclonal Antibody
CAT# AFG-PNB-15406
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD300d Polyclonal Antibody
CAT# AFG-PNB-15405
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD192 Polyclonal Antibody
CAT# AFG-PNB-15404
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD305 Polyclonal Antibody
CAT# AFG-PNB-15403
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD209 Polyclonal Antibody
CAT# AFG-PNB-15402
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD267 Polyclonal Antibody
CAT# AFG-PNB-15401
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD180 Polyclonal Antibody
CAT# AFG-PNB-15400
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD155 Polyclonal Antibody
CAT# AFG-PNB-15399
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD232 Polyclonal Antibody
CAT# AFG-PNB-15398
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD240d Polyclonal Antibody
CAT# AFG-PNB-15397
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® SIRP-α1/β1 Polyclonal Antibody
CAT# AFG-PNB-15396
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® Ox40L Polyclonal Antibody
CAT# AFG-PNB-15395
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD300c Polyclonal Antibody
CAT# AFG-PNB-15394
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD158a Polyclonal Antibody
CAT# AFG-PNB-15393
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD244 Polyclonal Antibody
CAT# AFG-PNB-15392
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® BST-2 Polyclonal Antibody
CAT# AFG-PNB-15391
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD138 Polyclonal Antibody
CAT# AFG-PNB-15390
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® Ox40 Polyclonal Antibody
CAT# AFG-PNB-15389
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD101 Polyclonal Antibody
CAT# AFG-PNB-15388
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD98 Polyclonal Antibody
CAT# AFG-PNB-15387
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD96 Polyclonal Antibody
CAT# AFG-PNB-15386
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD93 Polyclonal Antibody
CAT# AFG-PNB-15385
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® LIR-1 Polyclonal Antibody
CAT# AFG-PNB-15384
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD85d Polyclonal Antibody
CAT# AFG-PNB-15383
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD66c/d Polyclonal Antibody
CAT# AFG-PNB-15382
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD53 Polyclonal Antibody
CAT# AFG-PNB-15381
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD42d/GPV Polyclonal Antibody
CAT# AFG-PNB-15380
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD39 Polyclonal Antibody
CAT# AFG-PNB-15379
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD36 Polyclonal Antibody
CAT# AFG-PNB-15378
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD33 Polyclonal Antibody
CAT# AFG-PNB-15377
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD21 Polyclonal Antibody
CAT# AFG-PNB-15376
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD19 Polyclonal Antibody
CAT# AFG-PNB-15375
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD13 Polyclonal Antibody
CAT# AFG-PNB-15374
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD6 Polyclonal Antibody
CAT# AFG-PNB-15373
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® PSGL-1 Polyclonal Antibody
CAT# AFG-PNB-15372
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD89 Polyclonal Antibody
CAT# AFG-PNB-15371
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® AID Polyclonal Antibody
CAT# AFG-PNB-15370
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® C4a/b Polyclonal Antibody
CAT# AFG-PNB-15369
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD292 Polyclonal Antibody
CAT# AFG-PNB-15368
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD85c Polyclonal Antibody
CAT# AFG-PNB-15367
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD47 Polyclonal Antibody
CAT# AFG-PNB-15366
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® HLA-DQB1/2 Polyclonal Antibody
CAT# AFG-PNB-15365
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® SAMHD1 Polyclonal Antibody
CAT# AFG-PNB-15364
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD316 Polyclonal Antibody
CAT# AFG-PNB-15363
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® NKp44 Polyclonal Antibody
CAT# AFG-PNB-15362
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD223 Polyclonal Antibody
CAT# AFG-PNB-15361
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD225 Polyclonal Antibody
CAT# AFG-PNB-15360
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD239 Polyclonal Antibody
CAT# AFG-PNB-15359
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD200 Polyclonal Antibody
CAT# AFG-PNB-15358
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® DCL-1 Polyclonal Antibody
CAT# AFG-PNB-15357
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD110 Polyclonal Antibody
CAT# AFG-PNB-15356
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® LIR-7 Polyclonal Antibody
CAT# AFG-PNB-15355
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD85f Polyclonal Antibody
CAT# AFG-PNB-15354
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD74 Polyclonal Antibody
CAT# AFG-PNB-15353
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD69 Polyclonal Antibody
CAT# AFG-PNB-15352
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD37 Polyclonal Antibody
CAT# AFG-PNB-15351
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD3-δ Polyclonal Antibody
CAT# AFG-PNB-15350
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD158b2/j Polyclonal Antibody
CAT# AFG-PNB-15349
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD163b Polyclonal Antibody
CAT# AFG-PNB-15348
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® RANKL Polyclonal Antibody
CAT# AFG-PNB-15347
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD148 Polyclonal Antibody
CAT# AFG-PNB-15346
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD169 Polyclonal Antibody
CAT# AFG-PNB-15345
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD166 Polyclonal Antibody
CAT# AFG-PNB-15344
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD42b Polyclonal Antibody
CAT# AFG-PNB-15343
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD38 Polyclonal Antibody
CAT# AFG-PNB-15342
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD71/TfR Polyclonal Antibody
CAT# AFG-PNB-15341
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD10 Polyclonal Antibody
CAT# AFG-PNB-15340
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD159a/c Polyclonal Antibody
CAT# AFG-PNB-15339
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD
AffiAB® CD201 Polyclonal Antibody
CAT# AFG-PNB-15338
Size: 1 Unit
For Price Contact info@affigen.com 0.0 USD