LRP Antibodies

LRP Antibodies are designed to detect and bind to Low-Density Lipoprotein Receptor-Related Proteins (LRPs), a family of receptors involved in various cellular processes, including lipid metabolism, endocytosis, signal transduction, and clearance of apoptotic cells. Among the most well-known members of this family are LRP1, LRP5, and LRP6, each playing distinct roles in cellular signaling and metabolism. 

Content of LRP Antibody

LRP Antibodies are produced by immunizing animals (e.g., rabbits, mice) with peptide sequences or protein fragments derived from different regions of LRPs, such as their extracellular or intracellular domains. These antibodies can be:

  • Polyclonal antibodies: Recognize multiple epitopes on the LRP protein, providing broad detection in a variety of experimental assays.
  • Monoclonal antibodies: Bind to a single, specific epitope on the LRP protein, ensuring high specificity and consistency in results.
Application of LRP Antibody

LRP Antibodies are widely used in cell biology, neuroscience, cancer research, and bone metabolism studies to investigate the roles of LRP receptors in cellular signaling and disease processes. Common applications include:

  • Wnt Signaling Research: LRP5 and LRP6 are essential co-receptors in the Wnt signaling pathway, which is involved in cellular growth, differentiation, and development. LRP Antibodies are used to study the role of these receptors in Wnt signaling activation, particularly in bone biology (osteoporosis) and cancer research. In cancer, aberrant Wnt signaling due to dysregulated LRP5/6 activity contributes to tumor growth and metastasis, making these antibodies critical in oncology research.
  • Neurodegenerative Disease Research: LRP1 plays a significant role in the central nervous system by mediating the clearance of amyloid-beta, a key factor in Alzheimer's disease pathogenesis. LRP Antibodies are used in neurobiology research to study how LRP1 expression is altered in neurodegenerative diseases, and how its interaction with amyloid-beta and other ligands contributes to disease progression.
  • Cardiovascular Research: LRP1 is also involved in regulating vascular homeostasis and lipid metabolism, and dysregulation of LRP1 is associated with atherosclerosis and cardiovascular disease. LRP Antibodies are applied to study the role of LRP1 in lipid clearance and how its dysfunction contributes to plaque formation in blood vessels.

LRP Antibodies are crucial tools in biomedical research, enabling the study of Low-Density Lipoprotein Receptor-Related Proteins (LRPs), which are involved in critical processes such as lipid metabolism, cellular signaling, and endocytosis. These antibodies are widely used across various fields, including neuroscience, cancer research, cardiovascular studies, and bone metabolism research. 

AffiAB® Rabbit anti-NLRP3 antibody
CAT# AFG-DDA-9769
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit Anti-LRP6 (pT1479) Antibody
CAT# AFG-DDA-8788
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit Anti-LRP1B Antibody
CAT# AFG-DDA-8694
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit Anti-LRP5 Antibody
CAT# AFG-DDA-8548
Size: 100 μL
351.50 351.5 USD
AffiAB® Rabbit Anti-LRP130 Antibody
CAT# AFG-DDA-6904
Size: 100 μL
317.30 317.3 USD
AffiAB® Rabbit Anti-LRP6 Antibody
CAT# AFG-DDA-6091
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-LRP2 Antibody
CAT# AFG-DDA-6035
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-LRP10 Antibody
CAT# AFG-DDA-5255
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit anti-LRP12 Antibody
CAT# AFG-DDA-1098
Size: 100 μL
274.55 274.55 USD
AffiAB® Rabbit anti-NLRP3 Antibody
CAT# AFG-DDA-0428
Size: 100 μL
256.50 256.5 USD
AffiAB® Rabbit anti-LRP11 Antibody
CAT# AFG-DDA-0171
Size: 100 μL
256.50 256.5 USD
AffiAB® NLRP9 Polyclonal Antibody
CAT# AFG-PAB-10202
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® NLRP7 Polyclonal Antibody
CAT# AFG-PAB-10201
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® NLRP6 Polyclonal Antibody
CAT# AFG-PAB-10200
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® NLRP4 Polyclonal Antibody
CAT# AFG-PAB-10199
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® NLRP3 Polyclonal Antibody
CAT# AFG-PAB-10198
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® NLRP2 Polyclonal Antibody
CAT# AFG-PAB-10197
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® NLRP12 Polyclonal Antibody
CAT# AFG-PAB-10196
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® NLRP10 Polyclonal Antibody
CAT# AFG-PAB-10195
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® NLRP1 Polyclonal Antibody
CAT# AFG-PAB-10194
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® LRPPRC Polyclonal Antibody
CAT# AFG-PAB-08565
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® LRPAP1 Polyclonal Antibody
CAT# AFG-PAB-08564
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® LRP8 Polyclonal Antibody
CAT# AFG-PAB-08563
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® LRP6 Polyclonal Antibody
CAT# AFG-PAB-08562
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® LRP5 Polyclonal Antibody
CAT# AFG-PAB-08561
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® LRP4 Polyclonal Antibody
CAT# AFG-PAB-08560
Size: 100 µL
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® LRP3 Polyclonal Antibody
CAT# AFG-PAB-08559
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® LRP2 Polyclonal Antibody
CAT# AFG-PAB-08558
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® LRP12 Polyclonal Antibody
CAT# AFG-PAB-08557
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® LRP11 Polyclonal Antibody
CAT# AFG-PAB-08556
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® LRP10 Polyclonal Antibody
CAT# AFG-PAB-08555
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® LRP1 Polyclonal Antibody
CAT# AFG-PAB-08554
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® Rabbit anti-NLRP3 Antibody
CAT# AFG-YBP-5757
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-LRP6 Antibody
CAT# AFG-YBP-4958
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-LRP5 Antibody
CAT# AFG-YBP-4957
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-LRP2 Antibody
CAT# AFG-YBP-4956
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-LRP130 Antibody
CAT# AFG-YBP-4955
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-LRP12 Antibody
CAT# AFG-YBP-4954
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-LRP11 Antibody
CAT# AFG-YBP-4953
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-LRP10 Antibody
CAT# AFG-YBP-4952
Size: 100 µL
457.00 457.0 USD
AffiAB® Anti-NLRP3 Antibody [SC06-23]
CAT# AFG-HB-2706
Size: 100 μL
496.50 496.5 USD
AffiAB® Anti-NLRP3 Antibody
CAT# AFG-HB-2705
Size: 100 μL
433.50 433.5 USD
AffiAB® Anti-LRP6 Antibody [A5E7]
CAT# AFG-HB-2340
Size: 100 μL
465.00 465.0 USD
AffiAB® Anti-LRP1 Antibody [SA0290]
CAT# AFG-HB-2339
Size: 100 μL
496.50 496.5 USD
AffiAB® Anti-LRP-1 Antibody [A4-F5]
CAT# AFG-HB-2338
Size: 100 μL
465.00 465.0 USD
AffiAB® Goat Anti-LRP4 / LRP10 Antibody
CAT# AFG-IVA-11986
Size: 100 µg
Terminal: N/A
746.15 746.15 USD
AffiAB® Anti-Nlrp9a
CAT# AFG-IVA-01726
Size: 100 µL
Terminal: N/A
683.45 683.45 USD
AffiAB® Anti-LRP6 Phospho-specific Antibody
CAT# AFG-IVA-01653
Size: 100 µg
Terminal: N/A
719.15 719.15 USD
AffiAB® Anti-LRP6 Antibody
CAT# AFG-IVA-01652
Size: 100 µg
Terminal: N/A
813.65 813.65 USD
AffiAB® LRP4 Rabbit Polyclonal Antibody
CAT# AFG-EKA-09284
Size: 100 µL
246.00 246.0 USD
AffiAB® LRP2 Rabbit Polyclonal Antibody
CAT# AFG-EKA-09283
Size: 100 µL
246.00 246.0 USD
AffiAB® LRP1B Rabbit Polyclonal Antibody
CAT# AFG-EKA-09282
Size: 100 µL
246.00 246.0 USD
AffiAB® LRP12 Rabbit Polyclonal Antibody
CAT# AFG-EKA-09281
Size: 100 µL
246.00 246.0 USD
AffiAB® LRP6 Rabbit Polyclonal Antibody
CAT# AFG-EKA-08493
Size: 100 µL
246.00 246.0 USD
AffiAB® LRP11 Rabbit Polyclonal Antibody
CAT# AFG-EKA-07291
Size: 100 µL
246.00 246.0 USD
AffiAB® LRP10 Rabbit Polyclonal Antibody
CAT# AFG-EKA-04964
Size: 100 µL
246.00 246.0 USD