IGF Antibodies

Insulin-like growth factors (IGFs) are a family of proteins with high structural similarity to insulin, primarily involved in growth and development. The two main types, IGF-1 and IGF-2, play essential roles in regulating cell proliferation, differentiation, and apoptosis through interactions with the IGF receptor (IGF-1R). IGF antibodies are specialized reagents used for the detection, quantification, and localization of IGF proteins in various biological systems. 

Content

IGF antibodies can be either monoclonal or polyclonal, each type designed to recognize specific epitopes on IGF proteins, including IGF-1, IGF-2, or their receptors. Monoclonal IGF antibodies target a single epitope, providing high specificity, while polyclonal antibodies bind to multiple epitopes, offering stronger signals in immunoassays. 

Applications of IGF Antibody
  • Aging and Longevity Studies: The IGF signaling pathway has been linked to aging and lifespan regulation. Lower levels of IGF-1 are associated with extended lifespan in various organisms. IGF antibodies allow researchers to study the mechanisms by which IGF-1 influences aging, especially in tissues like muscle, bone, and the cardiovascular system. These antibodies are used in IHC and Western blotting to quantify IGF-1 levels and correlate them with markers of aging.
  • Therapeutic Monitoring: In clinical settings, recombinant IGF-1 therapy is used for treating conditions such as growth hormone insensitivity syndrome (GHIS) and short stature. IGF antibodies are used to monitor patient responses to IGF-1 therapies by measuring circulating IGF levels. This ensures proper dosage and therapeutic effectiveness while minimizing side effects.
  • Cell Signaling Studies: IGF antibodies are instrumental in dissecting the signaling pathways activated by IGF-1 and IGF-2 through their interaction with IGF-1R. These signaling pathways, particularly the PI3K-Akt and MAPK pathways, play a significant role in cellular proliferation and survival. Researchers use IGF antibodies in Western blotting and immunoprecipitation assays to study the activation of downstream signaling components, such as phosphorylated Akt and Erk, after IGF receptor stimulation.
  • Immunohistochemistry (IHC) and Flow Cytometry: IGF antibodies are used in IHC to detect IGF-1 and IGF-2 in tissue sections, providing spatial information on IGF expression in various organs. This is particularly important in cancer research, where IGF overexpression correlates with aggressive tumor behavior. IGF antibodies are also used in flow cytometry to quantify IGF levels in different cell types, offering insights into IGF-driven cell signaling in both normal and pathological conditions.

IGF antibodies are vital tools in the study of the IGF signaling axis, which plays a pivotal role in cell growth, development, and metabolism. These antibodies are essential in cancer research, metabolic disease studies, aging research, and developmental biology. 

AffiAB® Mouse anti-IGF2 Antibody
CAT# AFG-DDA-9632
Size: 100 μL
284.05 284.05 USD
AffiAB® Mouse anti-IGF2 Antibody
CAT# AFG-DDA-9606
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-IGF2BP2 Antibody
CAT# AFG-DDA-9319
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit Anti-IGFBP7 Antibody
CAT# AFG-DDA-8672
Size: 100 μL
284.05 284.05 USD
351.50 351.5 USD
332.50 332.5 USD
AffiAB® Rabbit Anti-IGF1 Receptor Antibody
CAT# AFG-DDA-7509
Size: 100 μL
324.90 324.90000000000003 USD
AffiAB® Rabbit Anti-IGF1 Receptor Antibody
CAT# AFG-DDA-7363
Size: 100 μL
319.20 319.2 USD
AffiAB® Rabbit Anti-IGFBP3 Antibody
CAT# AFG-DDA-7303
Size: 100 μL
319.20 319.2 USD
AffiAB® Rabbit Anti-IGF1 Antibody
CAT# AFG-DDA-7267
Size: 100 μL
319.20 319.2 USD
AffiAB® Rabbit Anti-IGF1 Receptor Antibody
CAT# AFG-DDA-7026
Size: 100 μL
319.20 319.2 USD
319.20 319.2 USD
AffiAB® Rabbit Anti-IGFBP5 Antibody
CAT# AFG-DDA-5879
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-IGFBP4 Antibody
CAT# AFG-DDA-5878
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-IGF2BP1 Antibody
CAT# AFG-DDA-5877
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-IGFN1 Antibody
CAT# AFG-DDA-5528
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-IGFBP3 Antibody
CAT# AFG-DDA-5333
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-IGFBP3 (pS183) Antibody
CAT# AFG-DDA-5288
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-IGF1 Antibody
CAT# AFG-DDA-5227
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-PIGF Antibody
CAT# AFG-DDA-5021
Size: 100 μL
308.75 308.75 USD
AffiAB® Rabbit Anti-IGF2BP3 Antibody
CAT# AFG-DDA-4619
Size: 100 μL
300.20 300.2 USD
AffiAB® Rabbit anti-IGF2BP2 Antibody
CAT# AFG-DDA-3590
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-IGFBP2 Antibody
CAT# AFG-DDA-3330
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-IGF2 Antibody
CAT# AFG-DDA-3244
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-IGFL2 Antibody
CAT# AFG-DDA-2397
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-IGFBP1 Antibody
CAT# AFG-DDA-1260
Size: 100 μL
274.55 274.55 USD
AffiAB® Rabbit anti-IGF2BP3 Antibody
CAT# AFG-DDA-0809
Size: 100 μL
256.50 256.5 USD
AffiAB® Rabbit anti-IGFBP1 Antibody
CAT# AFG-DDA-0334
Size: 100 μL
256.50 256.5 USD
AffiAB® FIGF Polyclonal Antibody
CAT# AFG-PAB-16438
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® PIGF Polyclonal Antibody
CAT# AFG-PAB-11440
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGFN1 Polyclonal Antibody
CAT# AFG-PAB-07340
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGFL3 Polyclonal Antibody
CAT# AFG-PAB-07339
Size: 100 µL
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGFBP7 Polyclonal Antibody
CAT# AFG-PAB-07338
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGFBP6 Polyclonal Antibody
CAT# AFG-PAB-07337
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGFBP5 Polyclonal Antibody
CAT# AFG-PAB-07336
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® IGFBP4 Polyclonal Antibody
CAT# AFG-PAB-07335
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® Phospho-IGFBP3 - Ser183 Polyclonal Antibody
CAT# AFG-PAB-07334
Size: 100ul
Conjugation: Unconjugated
625.00 625.0 USD
AffiAB® Phospho-IGFBP3 - S183 Polyclonal Antibody
CAT# AFG-PAB-07333
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGFBP3 Polyclonal Antibody
CAT# AFG-PAB-07332
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGFBP2 Polyclonal Antibody
CAT# AFG-PAB-07331
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® IGFBP1 Polyclonal Antibody
CAT# AFG-PAB-07330
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGFALS Polyclonal Antibody
CAT# AFG-PAB-07329
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® Phospho-IGF2R - Ser2409 Polyclonal Antibody
CAT# AFG-PAB-07328
Size: 100ul
Conjugation: Unconjugated
625.00 625.0 USD
AffiAB® Phospho-IGF2R - S2409 Polyclonal Antibody
CAT# AFG-PAB-07327
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGF2R Polyclonal Antibody
CAT# AFG-PAB-07326
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGF2BP3 Polyclonal Antibody
CAT# AFG-PAB-07325
Size: 150 µL
Conjugation: Unconjugated
1,112.50 1112.5 USD
AffiAB® IGF2BP2 Polyclonal Antibody
CAT# AFG-PAB-07324
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGF2BP1 Polyclonal Antibody
CAT# AFG-PAB-07323
Size: 100 µL
Conjugation: Unconjugated
533.50 533.5 USD
AffiAB® IGF2 Polyclonal Antibody
CAT# AFG-PAB-07322
Size: 100 µL (100 µg)
Conjugation: Unconjugated
682.00 682.0 USD
AffiAB® IGF1R/INSR Polyclonal Antibody
CAT# AFG-PAB-07321
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® Phospho-IGF1R/INSR - Y1161 Polyclonal Antibody
CAT# AFG-PAB-07320
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® Phospho-IGF1R - Tyr1161 Polyclonal Antibody
CAT# AFG-PAB-07319
Size: 100ul
Conjugation: Unconjugated
625.00 625.0 USD
AffiAB® Phospho-IGF1R - Tyr1165/Tyr1166 Polyclonal Antibody
CAT# AFG-PAB-07318
Size: 100ul
Conjugation: Unconjugated
625.00 625.0 USD
AffiAB® Phospho-IGF1R - Tyr1346 Polyclonal Antibody
CAT# AFG-PAB-07317
Size: 100ul
Conjugation: Unconjugated
625.00 625.0 USD
AffiAB® Phospho-IGF1R - Tyr1280 Polyclonal Antibody
CAT# AFG-PAB-07316
Size: 100ul
Conjugation: Unconjugated
625.00 625.0 USD
AffiAB® IGF1R - Ab-1161 Polyclonal Antibody
CAT# AFG-PAB-07315
Size: 100ul
Conjugation: Unconjugated
530.50 530.5 USD
AffiAB® IGF1R - Ab-1346 Polyclonal Antibody
CAT# AFG-PAB-07314
Size: 100ul
Conjugation: Unconjugated
530.50 530.5 USD
AffiAB® IGF1R - Ab-1280 Polyclonal Antibody
CAT# AFG-PAB-07313
Size: 100ul
Conjugation: Unconjugated
530.50 530.5 USD
AffiAB® IGF1R - Ab-1165/1166 Polyclonal Antibody
CAT# AFG-PAB-07312
Size: 100ul
Conjugation: Unconjugated
530.50 530.5 USD
AffiAB® Phospho-IGF1R - Y1165/Y1166 Polyclonal Antibody
CAT# AFG-PAB-07311
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® Phospho-IGF1R - Y1346 Polyclonal Antibody
CAT# AFG-PAB-07310
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGF1R Polyclonal Antibody
CAT# AFG-PAB-07309
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® IGF1 Polyclonal Antibody
CAT# AFG-PAB-07308
Size: 100 µg
Conjugation: Unconjugated
335.50 335.5 USD
AffiAB® Rabbit anti-PIGF Antibody
CAT# AFG-YBP-6358
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFN1 Antibody
CAT# AFG-YBP-4446
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFL2 Antibody
CAT# AFG-YBP-4445
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFBP5 Antibody
CAT# AFG-YBP-4444
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFBP4 Antibody
CAT# AFG-YBP-4443
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFBP3 Antibody
CAT# AFG-YBP-4442
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFBP3 Antibody
CAT# AFG-YBP-4441
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFBP3 (pS183) Antibody
CAT# AFG-YBP-4440
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFBP2 Antibody
CAT# AFG-YBP-4439
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFBP1 Antibody
CAT# AFG-YBP-4438
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGFBP1 Antibody
CAT# AFG-YBP-4437
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGF2BP3 Antibody
CAT# AFG-YBP-4436
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGF2BP3 Antibody
CAT# AFG-YBP-4435
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGF2BP2 Antibody
CAT# AFG-YBP-4434
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGF2BP1 Antibody
CAT# AFG-YBP-4433
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGF2 Antibody
CAT# AFG-YBP-4432
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGF1 Receptor Antibody
CAT# AFG-YBP-4431
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGF1 Receptor Antibody
CAT# AFG-YBP-4430
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGF1 Receptor Antibody
CAT# AFG-YBP-4429
Size: 100 µL
457.00 457.0 USD
457.00 457.0 USD
457.00 457.0 USD
457.00 457.0 USD
AffiAB® Rabbit anti-IGF1 Antibody
CAT# AFG-YBP-4425
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-IGF1 Antibody
CAT# AFG-YBP-4424
Size: 100 µL
457.00 457.0 USD
AffiAB® Anti-IGFBP2 Antibody [JU37-46]
CAT# AFG-HB-2010
Size: 100 μL
496.50 496.5 USD
AffiAB® Anti-IGF2R/M6PR Antibody
CAT# AFG-HB-2009
Size: 100 μL
433.50 433.5 USD
AffiAB® Anti-IGF2BP2 Antibody [JE56-58]
CAT# AFG-HB-2008
Size: 100 μL
496.50 496.5 USD
AffiAB® Anti-IGF2 Antibody [JJ092-3]
CAT# AFG-HB-2007
Size: 100 μL
496.50 496.5 USD
AffiAB® Anti-IGF1R Antibody [D5-G2]
CAT# AFG-HB-2006
Size: 100 μL
465.00 465.0 USD
AffiAB® Anti-IGF1R Antibody
CAT# AFG-HB-2005
Size: 100 μL
433.50 433.5 USD
AffiAB® Anti-IGF1 (E peptide) Antibody
CAT# AFG-HB-2004
Size: 100 μL
433.50 433.5 USD
AffiAB® IGF1R Antibody (Phospho-Tyr1346)
CAT# AFG-IVA-15538
Size: 100 µg
Terminal: N/A
719.15 719.15 USD
AffiAB® IGF1R Antibody (Phospho-Tyr1161)
CAT# AFG-IVA-15535
Size: 100 µL
Terminal: N/A
597.65 597.65 USD
AffiAB® IGF1R Antibody - PE Conjugated
CAT# AFG-IVA-15535
Size: 100 Tests
Terminal: N/A
921.65 921.65 USD
AffiAB® IGF1R Antibody - HRP Conjugated
CAT# AFG-IVA-15534
Size: 100 µg
Terminal: N/A
719.15 719.15 USD
AffiAB® IGF1R Antibody - FITC Conjugated
CAT# AFG-IVA-15533
Size: 100 µg
Terminal: N/A
719.15 719.15 USD
AffiAB® IGF1R Antibody - Biotin Conjugated
CAT# AFG-IVA-15532
Size: 100 µg
Terminal: N/A
719.15 719.15 USD