TYROSIN Antibodies

Tyrosine is one of the 20 standard amino acids and plays a critical role in several biological processes, particularly in protein synthesis, enzyme activity regulation, and signal transduction. In proteins, tyrosine residues can undergo phosphorylation, a post-translational modification that is central to cellular signaling pathways, especially in receptor-mediated signal transduction. Tyrosine phosphorylation is a key event in the activation of growth factors, cytokine receptors, and many intracellular kinases, making it crucial for regulating cell growth, proliferation, and differentiation.

Molecular Applications of Tyrosine Antibodies
  • Immune Signaling: Tyrosine phosphorylation plays a critical role in immune cell activation, particularly in T-cell and B-cell receptor signaling. Tyrosine antibodies help researchers study how these phosphorylation events regulate immune responses, which is essential for understanding autoimmune diseases and developing immunotherapies.
  • Metabolic Regulation: Insulin signaling relies on tyrosine phosphorylation of the insulin receptor and downstream effectors like IRS-1. Tyrosine antibodies are used to investigate insulin signaling and how dysregulation contributes to metabolic diseases like diabetes and obesity.
  • Neuroscience: In the nervous system, tyrosine phosphorylation regulates synaptic plasticity, neuron growth, and neurotransmitter release. Antibodies against phosphorylated tyrosine residues are applied in studies investigating neuronal signaling and neurodegenerative diseases.
Antibody Validation and Sensitivity

Tyrosine antibodies, especially those targeting phospho-tyrosine, are rigorously validated to ensure high sensitivity and specificity. Validation often involves testing with known positive controls (e.g., tyrosine-phosphorylated peptides or proteins) and negative controls (non-phosphorylated proteins) to confirm accurate detection.

  • Phospho-Specificity: Phospho-tyrosine antibodies are tested to ensure they specifically recognize phosphorylated tyrosine residues and do not cross-react with other phosphorylated amino acids (e.g., phospho-serine or phospho-threonine).
  • Species Cross-Reactivity: Tyrosine antibodies are validated for use in a wide range of species, including humans, mice, rats, and other model organisms.

Tyrosine antibodies, particularly those targeting phosphorylated tyrosine residues, are invaluable tools for studying protein phosphorylation and its regulatory role in signal transduction. These antibodies enable researchers to explore cellular pathways in cancer, immune regulation, metabolism, and neuroscience.

AffiAB® Mouse anti-Tyrosinase Antibody
CAT# AFG-DDA-9617
Size: 100 μL
284.05 284.05 USD
AffiAB® Mouse anti-Tyrosinase Antibody
CAT# AFG-DDA-9616
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit Anti-Tyrosine Hydroxylase Antibody
CAT# AFG-DDA-8477
Size: 100 μL
351.50 351.5 USD
AffiAB® Mouse Anti-Phosphotyrosine Antibody
CAT# AFG-DDA-8430
Size: 100 μL
347.70 347.7 USD
332.50 332.5 USD
AffiAB® Rabbit Anti-Tyrosine Hydroxylase Antibody
CAT# AFG-DDA-8116
Size: 100 μL
332.50 332.5 USD
324.90 324.90000000000003 USD
317.30 317.3 USD
AffiAB® Rabbit anti-Tyrosinase Antibody
CAT# AFG-DDA-1892
Size: 100 μL
284.05 284.05 USD
AffiAB® Tyrosinase Polyclonal Antibody
CAT# AFG-PAB-16100
Size: 100ul
Conjugation: Unconjugated
530.05 530.05 USD
AffiAB® Rabbit anti-Tyrosine Hydroxylase Antibody
CAT# AFG-YBP-8173
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-Tyrosine Hydroxylase Antibody
CAT# AFG-YBP-8172
Size: 100 µL
457.00 457.0 USD
457.00 457.0 USD
457.00 457.0 USD
457.00 457.0 USD
AffiAB® Rabbit anti-Tyrosinase Antibody
CAT# AFG-YBP-8168
Size: 100 µL
457.00 457.0 USD
AffiAB® Mouse anti-Phosphotyrosine Antibody
CAT# AFG-YBP-0173
Size: 100 µL
457.00 457.0 USD
496.50 496.5 USD
496.50 496.5 USD
AffiAB® Anti-Tyrosine Hydroxylase Antibody
CAT# AFG-HB-3980
Size: 100 μL
433.50 433.5 USD
AffiAB® Anti-Tyrosinase Antibody [JA52-11]
CAT# AFG-HB-3979
Size: 100 μL
496.50 496.5 USD
AffiAB® Anti-Tyrosinase Antibody [C2-B5]
CAT# AFG-HB-3978
Size: 100 μL
465.00 465.0 USD
AffiAB® Anti-Tyrosinase Antibody
CAT# AFG-HB-3977
Size: 100 μL
433.50 433.5 USD
496.50 496.5 USD
314.00 314.0 USD
AffiAB® Anti-Nitrotyrosine Purified [EM-30]
CAT# AFG-EXB-0497
Size: 0.1 mg
323.00 323.0 USD
AffiAB® Anti-Phosphotyrosine Purified [P-Tyr-01]
CAT# AFG-EXB-0181
Size: 0.1 mg
218.00 218.0 USD
AffiAB® tyrosine hydroxylase Antibody
CAT# AFG-IVA-00001
Size: 100 µg
665.15 665.15 USD
AffiAB® Anti-Phosphotyrosine Polyclonal Antibody
CAT# AFG-IVA-01802
Size: 100 µg
Terminal: N/A
854.15 854.15 USD
AffiAB® Anti-Phosphotyrosine Antibody
CAT# AFG-IVA-01801
Size: 100 µg
Terminal: N/A
813.65 813.65 USD