![AffiAB® Anti-Hu TCR Vdelta2 PE [B6]](/web/image/product.product/292883/image_1024/%5BAFG-XBO-2003%5D%20AffiAB%C2%AE%E2%80%8B%20Anti-Hu%20TCR%20Vdelta2%20PE%20%5BB6%5D?unique=0daa593)
Overview
TCR Vdelta2 is a variant of TCR delta chain, that is present on a major subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 (or Vgamma2/Vdelta2) T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors. They can recognize these antigens in an MHC-unrestricted manner. Similarly to NK cells, Vdelta2 T cells express MHC I receptors and killer Ig-like receptors, that are involved in tumor recognition and cytolysis. The potently cytotoxic subset of them is identified by cell surface expression of polysialyated CD56..
Species Reactivity
Human.
Antigen
TCR Vdelta2.
Negative Species
N/A.
Application
FC (QC tested) ) .
Immunogen
human recombinant TCR Vdelta2.
Clone
B6.
Format
PE.
Isotype
Mouse IgG1 kappa.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide.
Storage & Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.