![AffiAB® Anti-Hu TCR gamma/delta FITC [11F2]](/web/image/product.product/292868/image_1024/%5BAFG-XBO-1988%5D%20AffiAB%C2%AE%E2%80%8B%20Anti-Hu%20TCR%20gamma-delta%20FITC%20%5B11F2%5D?unique=0daa593)
Overview
The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression..
Species Reactivity
Human.
Antigen
TCR gamma/delta.
Negative Species
N/A.
Application
FC (QC tested) ) .
Immunogen
Purified CD3 antigen complex.
Clone
11F2.
Format
FITC.
Isotype
Mouse IgG1.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide.
Storage & Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.