![AffiAB® Anti-IRAK2 Antibody [JG36-23]](/web/image/product.product/74919/image_1024/%5BAFG-HB-2150%5D%20AffiAB%C2%AE%20Anti-IRAK2%20Antibody%20%5BJG36-23%5D%20?unique=1b95906)
AffiAB® Anti-IRAK2 Antibody [JG36-23]
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. IRAK2 has been shown to interact with TRAF6 and Myd88.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: O43187 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JG36-23
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human IRAK2 aa 30-270 / 625.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Immunology & Inflammation
Recommended dilutions
WB: 1:500-1:2, 000; IF-Cell: 1:50-1:200; IF-Tissue: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100; IP: 1:10-1:50
Molecular Weight
69 kDa
Subcellular location
Cytoplasm. Nucleus.
Positive control
PC-3M cell lysate, A549 cell lysate, HepG2 cell lysate, PC-3M, human tonsile tissue, human prostate carcinoma tissue, human heart tissue, Jurkat.