Overview
HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
Specificity:
The mouse monoclonal antibody L243 recognizes specifically an extracellular epitope on HLA-DR molecules, both peptide-loaded and empty.
Antigen
HLA-DR
Clone
L243
Species Reactivity
Dog, Non-human primates, Human
Negative Species
N/A
Isotype
Mouse IgG2a kappa
Immunogen
Human B lymphocytes
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
APC-Cy7
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide