Overview
TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy.
Specificity:
The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.
Antigen
TROP2
Clone
TrMab-6
Species Reactivity
Pig, Human
Negative Species
Mouse
Isotype
Mouse IgG2b kappa
Immunogen
TROP2-transfected CHO cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
APC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide