![AffiAB® Anti-HLA-DR APC [MEM-12]](/web/image/product.product/79852/image_1024/%5BAFG-EXB-0882%5D%20AffiAB%C2%AE%20Anti-HLA-DR%20APC%20%5BMEM-12%5D?unique=0daa593)
Overview
HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
Specificity:
The antibody MEM-12 recognizes a common extracellular epitope on human HLA-DR which is dependent on the association of alpha and beta chains. DR is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages) .
Antigen
HLA-DR
Clone
MEM-12
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
thymocyte membrane
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
APC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide