Overview
Immunoglobulin M (IgM) is produced as a 900 kDa pentamer, which is an efficient complement binder. This antibody type is produced initially in the immune response and it is the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. IgM concentration in blood is 0.12 g/l and its biological survival (plasma T1/2) is 5 days.
Specificity:
The antibody CH2 reacts with Fc fragment of human IgM.
Antigen
IgM
Clone
CH2
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Purified human IgM.
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
APC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide