![AffiAB® Anti-NG2 APC [7.1]](/web/image/product.product/79793/image_1024/%5BAFG-EXB-0823%5D%20AffiAB%C2%AE%20Anti-NG2%20APC%20%5B7.1%5D?unique=06fe5f0)
Overview
NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.
Specificity:
The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.
Antigen
NG2
Clone
7.1
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Human bone marrow stromal cells infected with SV-40
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
APC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide