![AffiAB® Anti-Hu IgD APC [IA6-2]](/web/image/product.product/79773/image_1024/%5BAFG-EXB-0803%5D%20AffiAB%C2%AE%20Anti-Hu%20IgD%20APC%20%5BIA6-2%5D?unique=06fe5f0)
Overview
Immunoglobulin D (IgD) is expressed on the surface of naive mature B cells, thus later than IgM, and is coexpressed with it then. Triggered by antigen binding, it signals through the CD79 complex to activate the B cells. Expression of IgD is lost after the isotype switch. Soluble IgD is present in very small amounts in the serum. IgD can bind to basophils and mast cells to activate them in an IgE-independent way to participate in respiratory immune defense.
Specificity:
The mouse monoclonal antibody IA6-2 recognizes human immunoglobulin D.
Antigen
IgD
Clone
IA6-2
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a kappa
Immunogen
Human IgD
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
APC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide