![AffiAB® Anti-Cytokeratins APC [C-11]](/web/image/product.product/79770/image_1024/%5BAFG-EXB-0800%5D%20AffiAB%C2%AE%20Anti-Cytokeratins%20APC%20%5BC-11%5D?unique=06fe5f0)
Overview
Cytokeratins are a subfamily of intermediate filaments and are characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Specificity:
The antibody C-11 reacts with cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are members of intermediate filaments subfamily intracellular proteins represented in epithelial tissues.
Antigen
Cytokeratins
Clone
C-11
Species Reactivity
Mammalian
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Keratin-enriched preparation from human epidermoid carcinoma cell line A431.
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
APC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide