![AffiAB® Anti-LRRC32 Purified [GARP5]](/web/image/product.product/79510/image_1024/%5BAFG-EXB-0540%5D%20AffiAB%C2%AE%20Anti-LRRC32%20Purified%20%5BGARP5%5D?unique=06fe5f0)
Overview
GARP (glycoprotein A repetitions predominant protein), also known as garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
Specificity:
The mouse monoclonal antibody GARP5 recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
Antigen
LRRC32
Clone
GARP5
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Purified human sGARP protein
Application
WB
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide