![AffiAB® Anti-CLIC5 Purified [CLIC5-02]](/web/image/product.product/79475/image_1024/%5BAFG-EXB-0505%5D%20AffiAB%C2%AE%20Anti-CLIC5%20Purified%20%5BCLIC5-02%5D?unique=d31c23b)
Overview
CLIC5a belongs to the family of chloride intracellular channel (CLIC) proteins, all sharing a highly conserved C terminus and variable N terminus. Human CLIC5 is transcribed in two isoforms, 32 kDa CLIC5a (251 amino acids) and 49 kDa CLIC5b (410 amino acids) . These proteins exist in a soluble form and their function as ion channels in vitro has not been fully confirmed in vivo. CLIC5a is a component of complexes of actin, ezrin, and several other actin-associated proteins and is important for functionality of actin-based structures.
Specificity:
Mouse monoclonal antibody CLIC5-02 recognizes CLIC5a, a 32 kDa intracellular protein which associates with proteins of actin complexes. Crossreactivity with CLIC5b was not determined.
Antigen
CLIC5
Clone
CLIC5-02
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2b kappa
Immunogen
KLH-conjugated peptide corresponding to the amino acids 160-173 of human CLIC5a (Cys-Ile-Asp-Ala-Asn-Thr-Ser-Asp-Lys-Gly-Ser-Arg-Arg coupled with KLH) .
Application
FC (QC tested), WB
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide