Available Sizes: 20 Tests, 50 Tests, 100 Tests, 200 Tests.
Background
Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and Antigen presentation, plays an important role in host defense and provides a link between innate and adaptive immunity.
Host
Mouse.
Species Reactivity
Human.
Synonyms
CLEC13D, CLEC13DL, MRC1L1, MMR, hMR.
Conjugation
APC.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
4360.