Filoviruses Antibodies 

Filoviruses antibodies are highly specific immunoglobulins designed to detect, neutralize, and study filoviruses, including Ebola virus and Marburg virus, which are highly pathogenic viruses that cause severe hemorrhagic fevers. These antibodies are vital in diagnosing, preventing, and treating viral infections by targeting specific viral components like surface glycoproteins. They also play a crucial role in research on viral pathogenesis, immunity, and the development of therapeutic interventions.

Types of Filoviruses Antibodies
  • Monoclonal Filoviruses Antibodies: These antibodies offer high specificity against key viral antigens such as glycoproteins. They are essential in both diagnostics and therapeutics.
  • Polyclonal Filoviruses Antibodies: These antibodies recognize multiple epitopes on the virus, enhancing detection sensitivity and providing broader reactivity.
  • Neutralizing Filoviruses Antibodies: Specifically designed to neutralize the virus, these antibodies target viral glycoproteins involved in host cell entry, blocking infection.
Mechanism of Action
  • Antigen Recognition: Filoviruses antibodies specifically bind to viral surface glycoproteins (e.g., GP, VP40) and matrix proteins (e.g., NP, VP24), disrupting their functions and preventing the virus from entering host cells.
  • Virus Neutralization: Neutralizing antibodies interfere with viral fusion by blocking the interaction between viral glycoproteins and host cell receptors, preventing the virus from infecting the host.
  • Detection in Immunoassays: Filoviruses antibodies are used in a variety of assays, including ELISA and lateral flow tests, to rapidly detect viral proteins or antigens in clinical samples.
Applications in Research and Medicine
  • Filoviruses Diagnosis: Filoviruses antibodies are critical in detecting the presence of viral antigens in biological samples using serological assays and antigen detection systems.
  • Therapeutic Antibody Development: Monoclonal antibodies (e.g., REGN-EB3, mAb114) have been developed for the treatment of Ebola virus disease, providing targeted therapeutic strategies.
  • Vaccine Evaluation: These antibodies are used to assess immune responses induced by vaccine candidates, ensuring efficacy against viral infection.

Filoviruses antibodies play a pivotal role in the fight against Ebola, Marburg, and related hemorrhagic fever viruses. With continuous advancements in antibody engineering, nanoparticle technology, and diagnostic methods, these antibodies are evolving to become more effective in detecting, neutralizing, and preventing viral infections. As a result, they hold significant promise for improving global health outcomes through more rapid and targeted diagnostics and therapeutics.

597.81 597.8100000000001 USD
AffiAB® Chimeric Anti-MARV GP mAb (c2D8)
CAT# AFG-BTB-155
Size: 100 μg
514.69 514.69 USD
AffiAB® Rabbit Anti-MARV VLP pAb
CAT# AFG-BTB-142
Size: 500 μg
295.00 295.0 USD
AffiAB® Rabbit Anti-EBOV Delta Peptide
CAT# AFG-BTB-135
Size: 100 μg
514.69 514.69 USD
AffiAB® Rabbit Anti-EBOV Soluble GP (sGP) pAb
CAT# AFG-BTB-134
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-EBOV VLP pAb
CAT# AFG-BTB-129
Size: 500 μg
514.69 514.69 USD
AffiAB® Rabbit Anti-RESTV GP pAb
CAT# AFG-BTB-118
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-BDBV GP pAb
CAT# AFG-BTB-117
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-MARV NP pAb
CAT# AFG-BTB-116
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-MARV GP pAb Biotinylated
CAT# AFG-BTB-115
Size: 100 μg
663.13 663.13 USD
AffiAB® Rabbit Anti-MARV GP pAb
CAT# AFG-BTB-114
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-MARV VP40 pAb
CAT# AFG-BTB-113
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-SUDV sGP pAb
CAT# AFG-BTB-112
Size: 100 μg
514.69 514.69 USD
AffiAB® Rabbit Anti-SUDV GP pAb
CAT# AFG-BTB-111
Size: 500 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-SUDV NP pAb
CAT# AFG-BTB-110
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-SUDV VP40 pAb
CAT# AFG-BTB-109
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-EBOV VP30 pAb
CAT# AFG-BTB-108
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-EBOV VP24 pAb
CAT# AFG-BTB-107
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-EBOV VP24 pAb
CAT# AFG-BTB-106
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-EBOV L-Polymerase pAb
CAT# AFG-BTB-105
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-EBOV VP35 pAb
CAT# AFG-BTB-104
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-EBOV GPΔmuc pAb
CAT# AFG-BTB-103
Size: 500 μg
514.69 514.69 USD
AffiAB® Rabbit Anti-EBOV GP pAb Biotinylated
CAT# AFG-BTB-102
Size: 100 μg
663.13 663.13 USD
AffiAB® Rabbit Anti-EBOV GP pAb
CAT# AFG-BTB-101
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-EBOV NP pAb
CAT# AFG-BTB-100
Size: 100 μg
544.38 544.38 USD
AffiAB® Rabbit Anti-EBOV VP40 pAb
CAT# AFG-BTB-099
Size: 100 μg
544.38 544.38 USD
AffiAB® Mouse Anti-SUDV GP mAb (16F6)
CAT# AFG-BTB-098
Size: 100 μg
514.69 514.69 USD
AffiAB® Human Anti-EBOV GP mAb (KZ52)
CAT# AFG-BTB-096
Size: 100 μg
544.38 544.38 USD
AffiAB® Anti-MARV GP chimeric mAb (2D8)
CAT# AFG-BTB-081
Size: 100 μg
514.69 514.69 USD
AffiAB® Anti-MARV GP chimeric mAb (SB-04)
CAT# AFG-BTB-080
Size: 100 μg
514.69 514.69 USD
AffiAB® Mouse Anti-MARV GP mAb (5C1)
CAT# AFG-BTB-079
Size: 100 μg
514.69 514.69 USD
AffiAB® Mouse Anti-MMARV VP40 mAb (6B1)
CAT# AFG-BTB-078
Size: 100 μg
514.69 514.69 USD
AffiAB® Mouse Anti-MARV VP40 mAb (1D1)
CAT# AFG-BTB-077
Size: 100 μg
514.69 514.69 USD
AffiAB® Mouse Anti-SUDV GP mAb (2H5)
CAT# AFG-BTB-076
Size: 100 μg
514.69 514.69 USD
AffiAB® Mouse Anti-SUDV VP40 mAb (1G10)
CAT# AFG-BTB-075
Size: 100 μg
514.69 514.69 USD
AffiAB® Mouse Anti-EBOV GP mAb (13C6)
CAT# AFG-BTB-074
Size: 100 μg
544.38 544.38 USD
AffiAB® Mouse Anti-EBOV GP mAb (4F3)
CAT# AFG-BTB-073
Size: 100 μg
544.38 544.38 USD
AffiAB® Mouse Anti-EBOV VP40 mAb (AE11)
CAT# AFG-BTB-072
Size: 100 μg
544.38 544.38 USD
AffiAB® Mouse Anti-EBOV VP40 mAb (5B12)
CAT# AFG-BTB-071
Size: 100 μg
544.38 544.38 USD
AffiAB® Mouse Anti-EBOV VP40 mAb (3G5)
CAT# AFG-BTB-070
Size: 100 μg
544.38 544.38 USD
AffiAB® Pan-filovirus Chimeric Anti-GP mAb
CAT# AFG-BTB-069
Size: 100 μg
597.81 597.8100000000001 USD
AffiAB® Pan-filovirus Mouse Anti-GP mAb
CAT# AFG-BTB-068
Size: 100 μg
597.81 597.8100000000001 USD
AffiAB® Rabbit Anti-MARV VLP Antiserum
CAT# AFG-BTB-064
Size: 250 μL
401.88 401.88 USD
AffiAB® Rabbit Anti-EBOV VLP Antiserum
CAT# AFG-BTB-063
Size: 250 μL
401.88 401.88 USD