ALKBH Antibodies

The ALKBH (AlkB Homolog) gene family encodes for enzymes that possess AlkB (alkylated DNA repair protein) domain, which is involved in the repair of alkylated DNA lesions. Alkylation damage in DNA can occur due to exposure to certain environmental agents or endogenous metabolic processes, and repairing such damage is essential for maintaining genomic stability.


There are several members in the ALKBH gene family, and they are involved in various cellular processes, including DNA repair, RNA modification, and other functions. One well-known member of this gene family is ALKBH5.


Here are some key points:


ALKBH5 (AlkB Homolog 5): ALKBH5 is involved in the demethylation of N6-methyladenosine (m6A), a reversible RNA modification. This enzyme plays a role in the regulation of RNA metabolism and has been implicated in processes such as mRNA stability and translation.


DNA Repair: While ALKBH5 is more well-known for its role in RNA demethylation, other members of the ALKBH family, such as ALKBH2 and ALKBH3, are primarily involved in the repair of alkylated DNA lesions.


Cancer and Disease Associations: Dysregulation of ALKBH genes has been associated with certain cancers and other diseases. For example, altered expression of ALKBH5 has been observed in various cancer types, suggesting its potential role in tumorigenesis.


Epigenetic Regulation: ALKBH enzymes contribute to epigenetic regulation by modifying RNA and, in some cases, by affecting DNA methylation patterns.

AffiAB® Anti-ALKBH5 Antibody
CAT# AFG-DDA-9772
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-ALKBH7 Antibody
CAT# AFG-DDA-3584
Size: 100 μL
284.05 284.05 USD
AffiAB® Rabbit anti-ALKBH3 Antibody
CAT# AFG-DDA-3192
Size: 100 μL
284.05 284.05 USD
AffiAB® ALKBH8 Polyclonal Antibody
CAT# AFG-PAB-00605
Size: 100 µL
Conjugation: Unconjugated
267.00 267.0 USD
AffiAB® ALKBH7 Polyclonal Antibody
CAT# AFG-PAB-00604
Size: 150 µL
Conjugation: Unconjugated
785.00 785.0 USD
AffiAB® ALKBH5 Polyclonal Antibody
CAT# AFG-PAB-00603
Size: 150 µL
Conjugation: Unconjugated
785.00 785.0 USD
AffiAB® ALKBH4 Polyclonal Antibody
CAT# AFG-PAB-00602
Size: 150 µL
Conjugation: Unconjugated
785.00 785.0 USD
AffiAB® ALKBH3 Polyclonal Antibody
CAT# AFG-PAB-00601
Size: 100 µg
Conjugation: Unconjugated
399.00 399.0 USD
AffiAB® ALKBH2 Polyclonal Antibody
CAT# AFG-PAB-00600
Size: 100 µL
Conjugation: Unconjugated
399.00 399.0 USD
AffiAB® ALKBH1 Polyclonal Antibody
CAT# AFG-PAB-00599
Size: 150 µL
Conjugation: Unconjugated
785.00 785.0 USD
AffiAB® Rabbit anti-ALKBH7 Antibody
CAT# AFG-YBP-0518
Size: 100 µL
457.00 457.0 USD
AffiAB® Rabbit anti-ALKBH3 Antibody
CAT# AFG-YBP-0517
Size: 100 µL
457.00 457.0 USD
AffiAB® ALKBH8 Antibody
CAT# AFG-IVA-00944
Size: 100 µL
Terminal: N/A
236.55 236.55 USD
AffiAB® ALKBH7 Antibody
CAT# AFG-IVA-00943
Size: 100 µL
Terminal: N/A
236.55 236.55 USD
AffiAB® ALKBH6 Antibody
CAT# AFG-IVA-00942
Size: 400 µL
Terminal: Middle region
369.55 369.55 USD
AffiAB® ALKBH5 Antibody
CAT# AFG-IVA-00941
Size: 400 µL
Terminal: Middle region
369.55 369.55 USD
AffiAB® ALKBH4 Antibody
CAT# AFG-IVA-00940
Size: 100 µg
Terminal: N/A
303.05 303.05 USD
AffiAB® ALKBH3 Antibody
CAT# AFG-IVA-00939
Size: 100 µg
Terminal: N/A
331.55 331.55 USD
AffiAB® ALKBH2 Antibody
CAT# AFG-IVA-00938
Size: 100 µL
Terminal: N/A
218.50 218.5 USD
AffiAB® ALKBH1 Antibody
CAT# AFG-IVA-00937
Size: 100 µL
Terminal: N/A
218.50 218.5 USD