ABCD Antibodies
ABCD1, ABCD2, ABCD3, and ABCD4 are members of the ABCD gene family. These genes encode for peroxisomal ATP-binding cassette transporters, which play a role in the import of fatty acids into peroxisomes. Peroxisomes are cellular organelles involved in lipid metabolism and various other functions.
Here are some key points about the ABCD gene family:
ABCD1 (ALD gene): Mutations in ABCD1 are associated with X-linked adrenoleukodystrophy (ALD), a genetic disorder affecting the nervous system and adrenal glands.
ABCD2: This gene is also known as adrenoleukodystrophy-related protein (ALDRP) and is involved in peroxisomal fatty acid beta-oxidation.
ABCD3: This gene encodes another member of the ABCD family and is associated with peroxisomal fatty acid beta-oxidation.
ABCD4: This gene is involved in the transport of cobalamin (vitamin B12) into the lysosomes.
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