Overview
Anti-HER2 (Phospho-Tyr1248) Rabbit Polyclonal Antibody.
Species Reactivity
Human, Mouse, Rat.
Host
Rabbit.
Specificity
This antibody detects endogenous human, mouse, and rat HER2 only when phosphorylated at tyrosine 1248.Accession no.: P04626, NP_001005862.1.
Target Name
HER2 (Phospho-Tyr1248).
Protein Name
Receptor tyrosine-protein kinase erbB-2.
Gene Name
ERBB2.
Gene ID
164870.
Localisation
[Isoform 1]: Cell membrane, Cytoplasm, perinuclear region. Nucleus. Note=Translocation to the nucleus requires endocytosis, probably endosomal sorting and is mediated by importin beta-1/KPNB1. Also detected in VPS35-positive endosome-to-TGN retrograde vesicles (PubMed:31138794).