AffiAB® 594 Conjugated Anti-S100 beta Antibody [SC57-02]

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CAT# AFG-HB-4274
Size: 100 μL

386.10 386.1 USD 386.10

386.10

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    AffiAB® 594 Conjugated Anti-S100 beta Antibody [SC57-02]

    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

    Antibody type

    Recombinant Rabbit monoclonal Antibody

    Uniprot ID

    SwissProt: P04271 Human; SwissProt: P50114 Mouse; SwissProt: P04631 Rat

    Recombinant

    YES

    Conjugation

    iFluor™ 594

    Host

    Rabbit

    Isotype

    IgG

    Clone

    SC57-02

    KO/KD

    N/A

    Species reactivity

    Human

    Tested applications

    IF-Tissue

    Predicted species reactivity

    N/A

    Immunogen

    Synthetic peptide within C-terminal human S100 beta.

    Storage

    Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

    Form

    Liquid

    Storage buffer

    Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS

    Concentration

    1 mg/mL.

    Purity

    Protein A affinity purified.

    Signal pathway

    N/A

    Recommended dilutions

    IF-Tissue: 1:50-1:200

    Molecular Weight

    11 kDa

    Subcellular location

    Cytoplasm, Nucleus.

    Positive control

    human malignant melanoma tissue, human meningioma tissue.

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