AffiAB® 594 Conjugated Anti-NeuN Antibody [SR45-07]

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CAT# AFG-HB-4273
Size: 100 μL

386.10 386.1 USD 386.10

386.10

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AffiAB® 594 Conjugated Anti-NeuN Antibody [SR45-07]

Neuronal nuclei (NeuN, Fox-3, RBFOX3) is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, and dentate nucleus neurons. This neuronal protein was originally identified by immunoreactivity with a monoclonal antibody also called NeuN. Using MS-analysis, NeuN was later identified as the Fox-3 gene product. Fox-3 contains an RNA recognition motif and functions as a splicing regulator. Fox-3 regulates alternative splicing of NumB, promoting neuronal differentiation during development.

Antibody type

Recombinant Rabbit monoclonal Antibody

Uniprot ID

SwissProt: A6NFN3 Human; SwissProt: Q8BIF2 Mouse; Unigene:143966 Rat

Recombinant

YES

Conjugation

iFluor™ 594

Host

Rabbit

Isotype

IgG

Clone

SR45-07

KO/KD

N/A

Species reactivity

Human, Mouse, Rat

Tested applications

IF-Tissue

Predicted species reactivity

N/A

Immunogen

Synthetic peptide within human NeuN aa 20-60.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

N/A

Recommended dilutions

IF-Tissue: 1:50

Molecular Weight

Predicted band size: 34 kDa

Subcellular location

Cytoplasm, Nucleus

Positive control

Mouse brain tissue.