AffiAB® 594 Conjugated Anti-NeuN Antibody [SR45-07]

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CAT# AFG-HB-4273
Size: 100 μL

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386.10

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    AffiAB® 594 Conjugated Anti-NeuN Antibody [SR45-07]

    Neuronal nuclei (NeuN, Fox-3, RBFOX3) is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, and dentate nucleus neurons. This neuronal protein was originally identified by immunoreactivity with a monoclonal antibody also called NeuN. Using MS-analysis, NeuN was later identified as the Fox-3 gene product. Fox-3 contains an RNA recognition motif and functions as a splicing regulator. Fox-3 regulates alternative splicing of NumB, promoting neuronal differentiation during development.

    Antibody type

    Recombinant Rabbit monoclonal Antibody

    Uniprot ID

    SwissProt: A6NFN3 Human; SwissProt: Q8BIF2 Mouse; Unigene:143966 Rat

    Recombinant

    YES

    Conjugation

    iFluor™ 594

    Host

    Rabbit

    Isotype

    IgG

    Clone

    SR45-07

    KO/KD

    N/A

    Species reactivity

    Human, Mouse, Rat

    Tested applications

    IF-Tissue

    Predicted species reactivity

    N/A

    Immunogen

    Synthetic peptide within human NeuN aa 20-60.

    Storage

    Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Form

    Liquid

    Storage buffer

    Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS

    Concentration

    1 mg/mL.

    Purity

    Protein A affinity purified.

    Signal pathway

    N/A

    Recommended dilutions

    IF-Tissue: 1:50

    Molecular Weight

    Predicted band size: 34 kDa

    Subcellular location

    Cytoplasm, Nucleus

    Positive control

    Mouse brain tissue.

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