AffiAB® 594 Conjugated Anti-Cytokeratin 7 Antibody [ST50-05]

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CAT# AFG-HB-4268
Size: 100 μL

386.10 386.1 USD 386.10

386.10

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    AffiAB® 594 Conjugated Anti-Cytokeratin 7 Antibody [ST50-05]

    Keratin, type II cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the KRT7 gene.Keratin 7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. Keratin-7 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.

    Antibody type

    Recombinant Rabbit monoclonal Antibody

    Uniprot ID

    SwissProt: P08729 Human; SwissProt: Q9DCV7 Mouse

    Recombinant

    YES

    Conjugation

    iFluor™ 594

    Host

    Rabbit

    Isotype

    IgG

    Clone

    ST50-05

    KO/KD

    N/A

    Species reactivity

    Human, Mouse

    Tested applications

    IF-Cell, IF-Tissue

    Predicted species reactivity

    N/A

    Immunogen

    Synthetic peptide within Human Cytokeratin 7 aa 18-67.

    Storage

    Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

    Form

    Liquid

    Storage buffer

    Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.

    Concentration

    1 mg/mL.

    Purity

    Protein A affinity purified.

    Signal pathway

    N/A

    Recommended dilutions

    IF-Cell: 1:100; IF-Tissue: 1:200-1:500

    Molecular Weight

    51 kDa

    Subcellular location

    Cytoplasm.

    Positive control

    Human breast tissue, human liver tissue, SK-Br-3.

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