AffiAB® 594 Conjugated Anti-Cytokeratin 7 Antibody [ST50-05]

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CAT# AFG-HB-4268
Size: 100 μL

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AffiAB® 594 Conjugated Anti-Cytokeratin 7 Antibody [ST50-05]

Keratin, type II cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the KRT7 gene.Keratin 7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. Keratin-7 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.

Antibody type

Recombinant Rabbit monoclonal Antibody

Uniprot ID

SwissProt: P08729 Human; SwissProt: Q9DCV7 Mouse

Recombinant

YES

Conjugation

iFluor™ 594

Host

Rabbit

Isotype

IgG

Clone

ST50-05

KO/KD

N/A

Species reactivity

Human, Mouse

Tested applications

IF-Cell, IF-Tissue

Predicted species reactivity

N/A

Immunogen

Synthetic peptide within Human Cytokeratin 7 aa 18-67.

Storage

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

N/A

Recommended dilutions

IF-Cell: 1:100; IF-Tissue: 1:200-1:500

Molecular Weight

51 kDa

Subcellular location

Cytoplasm.

Positive control

Human breast tissue, human liver tissue, SK-Br-3.