AffiAB® 594 Conjugated Anti-Cytokeratin 7 Antibody [ST50-05]
Keratin, type II cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the KRT7 gene.Keratin 7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. Keratin-7 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
Recombinant Rabbit monoclonal Antibody
SwissProt: P08729 Human; SwissProt: Q9DCV7 Mouse
Predicted species reactivity
Synthetic peptide within Human Cytokeratin 7 aa 18-67.
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.
Protein A affinity purified.
IF-Cell: 1:100; IF-Tissue: 1:200-1:500
Human breast tissue, human liver tissue, SK-Br-3.