AffiAB® 594 Conjugated Anti-Cytokeratin 10 Antibody [ST05-43]
Keratin, type I cytoskeletal 10 also known as cytokeratin-10 (CK-10) or keratin-10 (K10) is a protein that in humans is encoded by the KRT10 gene.] Keratin 10 is a type I keratin.Keratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P13645 Human; SwissProt: Q6IFW6 Rat
Recombinant
YES
Conjugation
iFluor™ 594
Host
Rabbit
Isotype
IgG
Clone
ST05-43
KO/KD
N/A
Species reactivity
Human, Rat
Tested applications
IF-Tissue
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human Cytokeratin 10 aa 541-584 / 584.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
IF-Tissue: 1:100-1:400
Molecular Weight
Predicted band size: 59 kDa
Subcellular location
Cytoplasm, secreted.
Positive control
Human skin tissue, rat skin tissue.