AffiAB® 488 Conjugated Anti-E-Cadherin Antibody [SY0287]

https://www.affiab.com/web/image/product.template/116622/image_1920?unique=136d80a

CAT# AFG-HB-4245
Size: 100 μL

386.10 386.1 USD 386.10

386.10

For Price contact us on info@gentaur.com

    This combination does not exist.

    Terms and Conditions
    14-day money-back guarantee
    Shipping: 1-3 Weeks

    AffiAB® 488 Conjugated Anti-E-Cadherin Antibody [SY0287]

    Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin-6) , R-cadherin, B-cadherin, E/P cadherin and cadherin-5. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function.

    Antibody type

    Recombinant Rabbit monoclonal Antibody

    Uniprot ID

    SwissProt: P12830 Human

    Recombinant

    YES

    Conjugation

    iFluor™ 488

    Host

    Rabbit

    Isotype

    IgG

    Clone

    SY0287

    KO/KD

    N/A

    Species reactivity

    Human

    Tested applications

    IF-Cell, FC

    Predicted species reactivity

    N/A

    Immunogen

    Synthetic peptide within Human E-Cadherin aa 591-640 / 882.

    Storage

    Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

    Form

    Liquid

    Storage buffer

    Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS

    Concentration

    1 mg/mL.

    Purity

    Protein A affinity purified.

    Signal pathway

    N/A

    Recommended dilutions

    IF-Cell: 1:100; FC: 1:50-1:1, 000

    Molecular Weight

    Predicted band size: 97 kDa

    Subcellular location

    Endosome, Cell membrane, trans-Golgi network, adherens junction.

    Positive control

    MCF-7, A431.

    Related Products

    Your Dynamic Snippet will be displayed here... This message is displayed because you did not provided both a filter and a template to use.