AffiAB® 488 Conjugated Anti-Cytokeratin 4 Antibody [SN74-03]

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CAT# AFG-HB-4239
Size: 100 μL

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    AffiAB® 488 Conjugated Anti-Cytokeratin 4 Antibody [SN74-03]

    Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene.Keratin 4 is a type II cytokeratin. It is specifically found in differentiated layers of the mucosal and esophageal epithelia together with keratin 13. Mutations in the genes encoding this protein have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia.

    Antibody type

    Recombinant Rabbit monoclonal Antibody

    Uniprot ID

    SwissProt: P19013 Human

    Recombinant

    YES

    Conjugation

    iFluor™ 488

    Host

    Rabbit

    Isotype

    IgG

    Clone

    SN74-03

    KO/KD

    N/A

    Species reactivity

    Human

    Tested applications

    IF-Tissue, IF-Cell

    Predicted species reactivity

    N/A

    Immunogen

    Recombinant protein within Human Cytokeratin 4 aa 395-520.

    Storage

    Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

    Form

    Liquid

    Storage buffer

    Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS

    Concentration

    1 mg/mL.

    Purity

    Protein A affinity purified.

    Signal pathway

    N/A

    Recommended dilutions

    IF-Tissue: 1:50; IF-Cell: 1:100

    Molecular Weight

    Predicted band size: 56 kDa

    Subcellular location

    Cell surface, intermediate filament cytoskeleton, nucleus.

    Positive control

    Human tonsil tissue, SK-Br-3.

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