AffiAB® 488 Conjugated Anti-Cytokeratin 4 Antibody [SN74-03]

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CAT# AFG-HB-4239
Size: 100 μL

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AffiAB® 488 Conjugated Anti-Cytokeratin 4 Antibody [SN74-03]

Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene.Keratin 4 is a type II cytokeratin. It is specifically found in differentiated layers of the mucosal and esophageal epithelia together with keratin 13. Mutations in the genes encoding this protein have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia.

Antibody type

Recombinant Rabbit monoclonal Antibody

Uniprot ID

SwissProt: P19013 Human

Recombinant

YES

Conjugation

iFluor™ 488

Host

Rabbit

Isotype

IgG

Clone

SN74-03

KO/KD

N/A

Species reactivity

Human

Tested applications

IF-Tissue, IF-Cell

Predicted species reactivity

N/A

Immunogen

Recombinant protein within Human Cytokeratin 4 aa 395-520.

Storage

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

N/A

Recommended dilutions

IF-Tissue: 1:50; IF-Cell: 1:100

Molecular Weight

Predicted band size: 56 kDa

Subcellular location

Cell surface, intermediate filament cytoskeleton, nucleus.

Positive control

Human tonsil tissue, SK-Br-3.