![AffiAB® 488 Conjugated Anti-Cytokeratin 4 Antibody [SN74-03]](/web/image/product.product/89447/image_1024/%5BAFG-HB-4239%5D%20AffiAB%C2%AE%20488%20Conjugated%20Anti-Cytokeratin%204%20Antibody%20%5BSN74-03%5D%20?unique=d31c23b)
AffiAB® 488 Conjugated Anti-Cytokeratin 4 Antibody [SN74-03]
Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene.Keratin 4 is a type II cytokeratin. It is specifically found in differentiated layers of the mucosal and esophageal epithelia together with keratin 13. Mutations in the genes encoding this protein have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P19013 Human
Recombinant
YES
Conjugation
iFluor™ 488
Host
Rabbit
Isotype
IgG
Clone
SN74-03
KO/KD
N/A
Species reactivity
Human
Tested applications
IF-Tissue, IF-Cell
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human Cytokeratin 4 aa 395-520.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
IF-Tissue: 1:50; IF-Cell: 1:100
Molecular Weight
Predicted band size: 56 kDa
Subcellular location
Cell surface, intermediate filament cytoskeleton, nucleus.
Positive control
Human tonsil tissue, SK-Br-3.