AffiAB® 488 Conjugated Anti-Cytokeratin 10 Antibody [ST05-43]

https://www.affiab.com/web/image/product.template/116609/image_1920?unique=d674372

CAT# AFG-HB-4232
Size: 100 μL

386.10 386.1 USD 386.10

386.10

For Price Contact info@affigen.com

This combination does not exist.

Terms and Conditions
30-day money-back guarantee
Shipping: 2-3 Business Days

AffiAB® 488 Conjugated Anti-Cytokeratin 10 Antibody [ST05-43]

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum.

Antibody type

Recombinant Rabbit monoclonal Antibody

Uniprot ID

SwissProt: P13645 Human; SwissProt: Q6IFW6 Rat

Recombinant

YES

Conjugation

iFluor™ 488

Host

Rabbit

Isotype

IgG

Clone

ST05-43

KO/KD

N/A

Species reactivity

Human, Rat

Tested applications

IF-Tissue

Predicted species reactivity

N/A

Immunogen

Synthetic peptide within Human Cytokeratin 10 aa 541-584 / 584.

Storage

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

N/A

Recommended dilutions

IF-Tissue: 1:400-1:500

Molecular Weight

Predicted band size: 59 kDa

Subcellular location

Cytoplasm.

Positive control

Human skin tissue, rat skin tissue.