AffiAB® 488 Conjugated Anti-Cytokeratin 10 Antibody [ST05-43]

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CAT# AFG-HB-4232
Size: 100 μL

386.10 386.1 USD 386.10

386.10

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    AffiAB® 488 Conjugated Anti-Cytokeratin 10 Antibody [ST05-43]

    Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum.

    Antibody type

    Recombinant Rabbit monoclonal Antibody

    Uniprot ID

    SwissProt: P13645 Human; SwissProt: Q6IFW6 Rat

    Recombinant

    YES

    Conjugation

    iFluor™ 488

    Host

    Rabbit

    Isotype

    IgG

    Clone

    ST05-43

    KO/KD

    N/A

    Species reactivity

    Human, Rat

    Tested applications

    IF-Tissue

    Predicted species reactivity

    N/A

    Immunogen

    Synthetic peptide within Human Cytokeratin 10 aa 541-584 / 584.

    Storage

    Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

    Form

    Liquid

    Storage buffer

    Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.

    Concentration

    1 mg/mL.

    Purity

    Protein A affinity purified.

    Signal pathway

    N/A

    Recommended dilutions

    IF-Tissue: 1:400-1:500

    Molecular Weight

    Predicted band size: 59 kDa

    Subcellular location

    Cytoplasm.

    Positive control

    Human skin tissue, rat skin tissue.

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