AffiAB® HRP Conjugated Anti-C-myc Antibody
Myc gene encodes for a transcription factor that is believed to regulate expression of 15% of all genes through binding on Enhancer Box sequences (E-boxes) and recruiting histone acetyltransferases (HATs) . c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. This c-Myc antibody detects endogenous levels of total c-Myc protein and is also for detection of Myc-tagged fusion proteins.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P01106 Human
Recombinant
NO
Conjugation
HRP-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
N/A
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human C-myc aa 390-439.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
PI3K-AKT, 衰老, Cancer, ErbB signaling pathway, JAK-STAT signaling pathway, Immunology & Inflammation, MAPK signaling pathway
Recommended dilutions
WB: 1:1, 000-1:2, 000
Molecular Weight
N/A
Subcellular location
Nucleus.
Positive control
Recombinant protein