AffiAB® HRP Conjugated Anti-Beta tubulin Antibody [1-B11]

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CAT# AFG-HB-4198
Size: 100 μL

486.60 486.6 USD 486.60

486.60

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AffiAB® HRP Conjugated Anti-Beta tubulin Antibody [1-B11]

Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are α-tubulin and β-tubulin. The beta-tubulin (relative molecular weight about 50 kDa) is counterpart of alpha-tubulin in tubulin heterodimer, it is coded by multiple tubulin genes and it is also posttranslationally modified. Heterogeneity of subunit is concentrated in C-terminal structural domain. Beta-Tubulin may have bound GTP or GDP. Under certain conditions β-tubulin can hydrolyze its bound GTP to GDP plus Pi, release the Pi, and exchange the GDP for GTP.

Antibody type

Mouse monoclonal Antibody

Uniprot ID

SwissProt: P07437 Human; SwissProt: P99024 Mouse; SwissProt: P69897 Rat

Recombinant

NO

Conjugation

HRP-conjugated

Host

Mouse

Isotype

IgG1

Clone

1-B11

KO/KD

N/A

Species reactivity

Human, Mouse, Rat, Zebrafish

Tested applications

WB, IHC-P

Predicted species reactivity

N/A

Immunogen

Synthetic peptide within Human Beta tubulin aa 46-95 / 444.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol.

Concentration

2 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

Parkinson’s disease, Huntington's disease, Amyotrophic lateral sclerosis, Alzheimer disease

Recommended dilutions

WB: 1:1, 000-1:5, 000 ; IHC-P: 1:50-1:200

Molecular Weight

50 kDa

Subcellular location

Cytoplasm, Cytoskeleton.

Positive control

NIH-3T3 cell lysate, PC-12 cell lysate, 293 cell lysate, Hela cell lysate, mouse fallopian tube tissue.