![AffiAB® Anti-ZNRF2 Antibody [JJ0924]](/web/image/product.product/89391/image_1024/%5BAFG-HB-4182%5D%20AffiAB%C2%AE%20Anti-ZNRF2%20Antibody%20%5BJJ0924%5D%20?unique=a48b62f)
AffiAB® Anti-ZNRF2 Antibody [JJ0924]
May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q8NHG8 Human; SwissProt: Q71FD5 Mouse; Entrez Gene: 362367 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JJ0924
KO/KD
N/A
Species reactivity
Mouse
Tested applications
WB, IHC-P
Predicted species reactivity
Human, Rat
Immunogen
Synthetic peptide within Human ZNRF2 aa 162-206 / 242.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 500
; IHC-P: 1:50-1:200
Molecular Weight
Predicted band size: 24 kDa
Subcellular location
Cell junction, Cell membrane, Cell projection, Endosome, Lysosome, Membrane, Synapse.
Positive control
Mouse testis tissue.