![AffiAB® Anti-YAP1 Antibody [SU33-06]](/web/image/product.product/89367/image_1024/%5BAFG-HB-4158%5D%20AffiAB%C2%AE%20Anti-YAP1%20Antibody%20%5BSU33-06%5D%20?unique=a48b62f)
AffiAB® Anti-YAP1 Antibody [SU33-06]
YAP1 (yes-associated protein 1) , also known as YAP or YAP65, is a protein that acts as a transcription coregulator that promotes transcription of genes involved in cellular proliferation and suppressing apoptotic genes. YAP1 is a component in the hippo signaling pathway which regulates organ size, regeneration, and tumorigenesis. YAP1 was first identified by virtue of its ability to associate with the SH3 domain of Yes and Src protein tyrosine kinases. YAP1 is a potent oncogene, which is amplified in various human cancers.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P46937 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
SU33-06
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human YAP1 aa 421-470 / 504.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000-1:2, 000; IF-Cell: 1:50-1:200; IF-Tissue: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100; IP: Use at an assay dependent concentration.
Molecular Weight
Predicted band size: 54 kDa
Subcellular location
Cytoplasm, Nucleus.
Positive control
Hela cell lysate, SiHa cell lysate, HepG2 cell lysate, Hela, HepG2, human colon carcinoma tissue, human breast carcinoma tissue, human kidney tissue, NIH/3T3.