AffiAB® Anti-Y14 Antibody

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CAT# AFG-HB-4157
Size: 100 μL

433.50 433.5 USD 433.50

433.50

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AffiAB® Anti-Y14 Antibody

RNA-binding protein 8A is a protein that in humans is encoded by the RBM8A gene. This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.

Antibody type

Rabbit polyclonal Antibody

Uniprot ID

SwissProt: Q9Y5S9 Human; SwissProt: Q9CWZ3 Mouse; SwissProt: Q27W01 Rat

Recombinant

NO

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

N/A

KO/KD

N/A

Species reactivity

Human, Mouse, Rat

Tested applications

WB, IF-Cell, IHC-P

Predicted species reactivity

N/A

Immunogen

Synthetic peptide within Human Y14 aa 125-174 / 174.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

N/A

Recommended dilutions

WB: 1:2, 000-1:5, 000; IHC-P: 1:200; IF-Cell: 1:50-1:200

Molecular Weight

Predicted band size: 20kDa

Subcellular location

Nucleus, Cytoplasm.

Positive control

Hela, HepG2, Jurkat, HCT116, SW480, MCF-7, RWPE-1, SW620, mouse kidney tissue, mouse heart tissue.