![AffiAB® Anti-Wnt2b Antibody [JB48-34]](/web/image/product.product/89346/image_1024/%5BAFG-HB-4137%5D%20AffiAB%C2%AE%20Anti-Wnt2b%20Antibody%20%5BJB48-34%5D%20?unique=a48b62f)
AffiAB® Anti-Wnt2b Antibody [JB48-34]
This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q93097 Human; SwissProt: O70283 Mouse; SwissProt: G3V7U3 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JB48-34
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, IF-Cell, IF-Tissue, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human Wnt2b aa 175-355 .
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:100-1:500; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
Predicted band size: 44 kDa
Subcellular location
Secreted. Extracellular region.
Positive control
Rat testis tissue lysate, Hela, LOVO, SHSY-5Y, rat testis tissue, human kidney tissue, mouse kidney tissue.