AffiAB® Anti-WNT2 Antibody
This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in the Wnt signaling pathway. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene. Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P09544 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human WNT2 aa 209-263.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Alzheimer disease
Recommended dilutions
WB: 1:1, 000-1:2, 000
; FC: 1:100-1:200
Molecular Weight
Predicted band size: 40 kDa
Subcellular location
Secreted, Extracellular matrix.
Positive control
PC-3M cell lysate, Mouse brain tissue, Jurkat cell lysate, Human lung tissue, Jurkat.