![AffiAB® Anti-WLS Antibody [A7C2]](/web/image/product.product/89341/image_1024/%5BAFG-HB-4132%5D%20AffiAB%C2%AE%20Anti-WLS%20Antibody%20%5BA7C2%5D%20?unique=b83e256)
AffiAB® Anti-WLS Antibody [A7C2]
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity) .
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q5T9L3 Human; SwissProt: Q6DID7 Mouse; SwissProt: Q6P689 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2b
Clone
A7C2
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human WLS aa 50-200/541.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:5, 000-1:20, 000; IF-Cell: 1:100
Molecular Weight
Predicted band size: 62 kDa
Subcellular location
Golgi apparatus membrane, Golgi apparatus membrane, Early endosome membrane, Endoplasmic reticulum membrane, Cell membrane, Cytoplasmic vesicle membrane.
Positive control
SH-SY5Y cell lysate, Hela cell lysate, mouse lung tissue lysate, rat brain tissue lysate, Hela, SH-SY5Y.