![AffiAB® Anti-WIPI1 Antibody [JE56-92]](/web/image/product.product/89340/image_1024/%5BAFG-HB-4131%5D%20AffiAB%C2%AE%20Anti-WIPI1%20Antibody%20%5BJE56-92%5D%20?unique=b83e256)
AffiAB® Anti-WIPI1 Antibody [JE56-92]
This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q5MNZ9 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE56-92
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human WIPI1 aa 20-120.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Autophagy Huntington's disease, Amyotrophic lateral sclerosis, Alzheimer disease
Recommended dilutions
WB: 1:500-1:1, 000
; IHC-P: 1:50-1:100
Molecular Weight
49 kDa
Subcellular location
Endosome, trans-Golgi network, cytoskeleton, clathrin-coated vesicle, preautophagosomal structure membrane.
Positive control
JAR cell lysates, human fetal skeletal muscle tissue.