AffiAB® Anti-VP40 Antibody [B6-A8]
Ebola virus VP40 Antibody is a high quality monoclonal Ebola virus VP40 antibody (also designated Ebola virus VP40 antibody) suitable for the detection of the Ebola virus VP40 protein of Ebola virus origin. Ebola virus VP40 Antibody (FE18) is available as the non-conjugated anti-Ebola virus VP40 antibody. Ebola virus is an enveloped, negative-stranded RNA virus which belongs to the family Filoviridae and has a distinctive morphology similar only to that of Marburg virus, but apparently has no antigenic characteristics of Marburg virus. Ebola virus is one of at least 18 known viruses capable of causing the viral hemorrhagic fever syndrome. Its genome is a nonsegmented RNA strand with seven structural proteins which include the major nucleoprotein (NP) , glycoprotein (GP) and L protein, in addition to four other proteins: VP40, VPX, VP30 and VP24. All the proteins are encoded by monocistronic mRNA transcripts complementary to virion RNA. Only GP, the major protein of the surface spikes, is glycosylated.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: X5H596 Zaire ebolavirus; SwissProt: Q05128 Zaire ebolavirus; SwissProt: Q77DJ6 Zaire ebolavirus; SwissProt: Q2PDK5 Zaire ebolavirus
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
B6-A8
KO/KD
N/A
Species reactivity
N/A
Tested applications
ELISA
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Zaire ebolavirus VP40 aa 260-300.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein G affinity purified.
Signal pathway
N/A
Recommended dilutions
ELISA: 1:10, 000.
Molecular Weight
N/A
Subcellular location
N/A
Positive control
N/A