AffiAB® Anti-Vitronectin Antibody [ST49-02]

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CAT# AFG-HB-4101
Size: 100 μL

496.50 496.5 USD 496.50

496.50

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AffiAB® Anti-Vitronectin Antibody [ST49-02]

Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

Antibody type

Recombinant Rabbit monoclonal Antibody

Uniprot ID

SwissProt: P04004 Human; SwissProt: P29788 Mouse; SwissProt: Q3KR94 Rat

Recombinant

YES

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

ST49-02

KO/KD

N/A

Species reactivity

Human, Mouse, Rat

Tested applications

WB, IF-Cell, IF-Tissue, IHC-P

Predicted species reactivity

N/A

Immunogen

Synthetic peptide within Human Vitronectin aa 429-478 / 478.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

Cardiovascular, PI3K-AKT

Recommended dilutions

WB: 1:1, 000-1:5, 000; IF-Cell: 1:50-1:200; IF-Tissue: 1:50-1:200; IHC-P: 1:50-1:400

Molecular Weight

Predicted band size: 54 kDa

Subcellular location

Secreted.

Positive control

Human liver tissue lysate, human serum lysate, A431, A549, HepG2, MCF-7, human liver tissue, mouse liver tissue, mouse skin tissue, human skin tissue, human skin tissue, rat skin tissue.