AffiAB® Anti-Vitamin K-dependent protein C Antibody
Protein C is a Vitamin K-dependent glycoprotein that is produced in the liver. Protein C is similar to the prothrombin group of blood coagulation factors in its primary structure. Normal protein C concentration in human plasma is approximately 1-3 ng/ml and the proenzyme concentration is approximately 3?g/ml. Protein C regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Protein C deficiency is associated with inherited thrombophilia, ecchymotic skin lesions.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P04070 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human Vitamin K-dependent protein C aa 412-461 / 461.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Cardiovascular
Recommended dilutions
WB: 1:1, 000
Molecular Weight
52/80 kDa
Subcellular location
Secretory protein
Positive control
K562, human plasma