AffiAB® Anti-VGluT1 Antibody [A7A3]
Vesicular glutamate transporter 1 (VGLUT1) is a protein that in humans is encoded by the SLC17A7 gene. The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q9P2U7 Human; SwissProt: Q3TXX4 Mouse; SwissProt: Q62634 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG3
Clone
A7A3
KO/KD
N/A
Species reactivity
Mouse, Rat, Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human VGluT1 aa 501-550 / 560.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein G affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000
Molecular Weight
Predicted band size: 62 kDa
Subcellular location
Synaptic vesicle membrane, Membrane, Synaptosome.
Positive control
Rat brain tissue lysates, mouse brain tissue lysates.